2-Chloro-4-methylthiazole CAS 26847-01-8
| CAS No. | 26847-01-8 |
| Molecular Formula | C4H4ClNS |
| Molecular Weight | 133.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-4-methylthiazole.
2-Chloro-4-methylthiazole (CAS 26847-01-8), molecular formula C4H4ClNS and molecular weight 133.60 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-4-methylthiazole (C4H4ClNS) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-4-methylthiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H4ClNS |
| Molecular Weight | 133.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-Chloro-4-methylisothiazole (CAS 1072-56-6)
- 2-Chloro-1,3-dimethyl-1H-imidazol-3-ium chloride (CAS 125376-11-6)
- 5-Chloro-4-methylthiazole (CAS 125402-79-1)
- 3-Chloro-5-methylisothiazole (CAS 14217-67-5)
- 2-Chloro-5-methylthiazole (CAS 33342-65-3)
- 4-Chloro-3-methylisothiazole (CAS 930-43-8)
- 5-Chloro-2-methyl-1,3-thiazole (CAS 57268-15-2)
- 5-Chloro-2-thiophenamine (CAS 63806-78-0)
Recommended Standards
- 5-(Chloromethyl)isothiazole (CAS 1710-68-5)
- 4-Chlorothiophen-2-amine (CAS 1427372-77-7)
- 3-Chlorothiophen-2-amine (CAS 491879-26-6)
- 4-(Chloromethyl)isothiazole (CAS 89033-79-4)
- 1-(1-Adamantyl)ethanol (CAS 26750-08-3)
- Ethyl (1S,2S)-4-hydroxy-2-methylcyclohexane-1-carboxylate (CAS 1940134-98-4)
- 1233641-89-8 2719AD 6-Cyclohexyl-2,9-dihydro-1H-carbazol-1-one C18H19NO (CAS 1233641-89-8)
- 5-(Benzyloxy)-4-chloro-2-methylpyrimidine (CAS 60438-06-4)
- 4-(5-Oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid (CAS 916169-50-1)
- Cis-3-((1H-imidazol-1-yl)methyl)-3,5-bis(4-chlorophenyl)-2-methylisoxazolidine (CAS 113614-50-9)
- (3-Chlorophenyl)(2,2-dimethoxyethyl)sulfane (CAS 205054-85-9)
- Ethyl ((3-chlorophenyl)(2-oxocyclooctyl)methyl)carbamate (CAS 478064-01-6)
- Amoxicillin Impurity 46 (CAS CATO-C4X-114846)
- Insulin Degludec Impurity 10 (CAS CATO-C4X-215710)
Why CATO?
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