Phloroglucinol Impurity 30 CAS 14227-17-9
| CAS No. | 14227-17-9 |
| Molecular Formula | C9H13NO3 |
| Molecular Weight | 183.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Phloroglucinol Impurity 30.
Phloroglucinol Impurity 30 (CAS 14227-17-9) is a certified pharmaceutical impurity reference standard with the molecular formula C9H13NO3 and a molecular weight of 183.20 g/mol.
The molecular framework of Phloroglucinol Impurity 30 (C9H13NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Phloroglucinol Impurity 30 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H13NO3 |
| Molecular Weight | 183.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 1 |
Related Phloroglucinol Standards
- Phloroglucinol EP Impurity O (CAS 137-19-9)
- Phloroglucinol Impurity 21 (CAS 106120-04-1)
- Phloroglucinol Impurity 15 (CAS 95-56-7)
- Phloroglucinol Impurity 14 (CAS 7051-16-3)
- Phloroglucinol Impurity 22 (CAS 106-40-1)
- Phloroglucinol Impurity 31 (CAS 1664-27-3)
- Phloroglucinol impurity 58 (CAS 1521-61-5)
- Phloroglucinol Impurity 32 (CAS 83-30-7)
Recommended Standards
- Nadifloxacin Impurity 2 (CAS 80076-46-6)
- Metaraminol Impurity 5 (CAS 20727-99-5)
- Vilanterol Impurity 23 (CAS CATO-C4X-193523)
- Carteolol Impurity 21 (CAS CATO-C4X-228721)
- Bortezomib Impurity 31 (CAS 1608986-16-8)
- N-Nitroso Aceclofenac EP Impurity A (CAS 66505-80-4)
- Abiraterone Impurity 42 (CAS CATO-C4X-107042)
- 2-Difluoromethoxy-6-(trifluoromethoxy)benzonitrile (CAS 1806331-24-7)
- Benzyl (cyanomethyl)carbamate (CAS 3589-41-1)
- 2-((2,5-Dimethoxyphenyl)thio)benzaldehyde (CAS 127905-39-9)
- 2-Methoxypropan-2-ol (CAS 72360-66-8)
- Gibberellin A24 (CAS 19427-32-8)
- Olmutinib (CAS 1353550-13-6)
- Myelin Basic Protein (85-99) Peptide Antagonist (CAS 444305-16-2)
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