Phloroglucinol Impurity 14 CAS 7051-16-3
| CAS No. | 7051-16-3 |
| Molecular Formula | C8H9ClO2 |
| Molecular Weight | 172.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Phloroglucinol Impurity 14 (C8H9ClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Phloroglucinol Impurity 14 (CAS 7051-16-3) is a certified pharmaceutical impurity reference standard with the molecular formula C8H9ClO2 and a molecular weight of 172.61 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Phloroglucinol Impurity 14 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9ClO2 |
| Molecular Weight | 172.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
Related Phloroglucinol Standards
- Phloroglucinol Impurity 15 (CAS 95-56-7)
- Phloroglucinol Impurity 22 (CAS 106-40-1)
- Phloroglucinol Impurity 31 (CAS 1664-27-3)
- Phloroglucinol Impurity 32 (CAS 83-30-7)
- Phloroglucinol Impurity 36 (CAS 530-55-2)
- Phloroglucinol EP Impurity O (CAS 137-19-9)
- Phloroglucinol EP Impurity I (CAS 87-65-0)
- Phloroglucinol Impurity 30 (CAS 14227-17-9)
Recommended Standards
- Tulobuterol Impurity 4 (CAS 59365-60-5)
- Opicapone Impurity 90 (CAS CATO-C4X-240490)
- Phenylephrine Impurity 48 (CAS 925430-39-3)
- Resmetirom impurity 64 (CAS 2375196-15-7)
- Avatrombopag impurity 129 (CAS CATO-C4X-2234129)
- Mosapride Impurity 49 (CAS CATO-C4X-104449)
- Nintedanib Impurity 109 (CAS CATO-C4X-1814109)
- Mexiletine Impurity 13 HCl (CAS 149961-12-6)
- 2-(2-Chloro-6-(trifluoromethyl)phenyl)acetic acid (CAS 886500-31-8)
- 3-Methoxy-4-{[(4-methoxyphenyl)carbamoyl]methoxy}benzoic acid (CAS 750613-33-3)
- 6-Benzyl-2,4-dichloro-5,6-dihydro-7H-pyrrolo[3,4-d]pyrimidin-7-one (CAS 1207368-82-8)
- 2-Methyl-2-[4-(2-methylpropoxy)phenyl]propanoic acid (CAS 1183487-83-3)
- 4-Bromo-1-(2-chloroethoxy)-2-methoxybenzene (CAS 877399-30-9)
- Insulin Degludec Impurity 16 (CAS CATO-C4X-215716)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com