Nadifloxacin Impurity 2 CAS 80076-46-6
| CAS No. | 80076-46-6 |
| Molecular Formula | C10H11F2N |
| Molecular Weight | 183.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Nadifloxacin Impurity 2 (C10H11F2N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Nadifloxacin Impurity 2 (CAS 80076-46-6), a pharmacopoeial impurity reference standard (molecular formula C10H11F2N, MW 183.20 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11F2N |
| Molecular Weight | 183.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Nadifloxacin Standards
- Nadifloxacin Impurity 3 (CAS 80076-50-2)
- Nadifloxacin Impurity 14 (CAS 458-11-7)
- Nadifloxacin Impurity 6 (CAS 87-13-8)
- Nadifloxacin Impurity 15 (CAS 64695-81-4)
- Nadifloxacin Impurity 1 (CAS 131190-82-4)
- Nadifloxacin isomer 1 (CAS 87488-29-7)
- Nadifloxacin Impurity A (CAS 80076-47-7)
- Nadifloxacin isomer 2 (CAS 130539-72-9)
Recommended Standards
- Vilanterol Impurity 23 (CAS CATO-C4X-193523)
- Phloroglucinol Impurity 30 (CAS 14227-17-9)
- Adrenaline Impurity 23 (CAS 1894824-44-2)
- Metaraminol Impurity 5 (CAS 20727-99-5)
- Neomycin Impurity 18 (CAS CATO-C4X-184518)
- Levocabastine impurity 19 (CAS CATO-C4X-228919)
- Cefprozil Impurity 55 (CAS CATO-C4X-149255)
- Sulfuryl chloride fluoride (CAS 13637-84-8)
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- 4-Bromo-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole (CAS 1353855-69-2)
- Methyl 2-(N-(3-cyanopropyl)-4-methylphenylsulfonamido)benzoate (CAS 105895-93-0)
- 4-((3-(Benzyloxy)-4-methoxybenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 677754-75-5)
- 5-Methyl-2-(trifluoromethyl)furan-3-sulfonyl chloride (CAS 306935-02-4)
- Bradykinin-Like Neuropeptide (Aplysia californica) (H-1654.0001) (CAS 165174-60-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com