Perampanel Impurity 38 CAS 142929-10-0
| CAS No. | 142929-10-0 |
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Perampanel Impurity 38 (CAS 142929-10-0), a pharmacopoeial impurity reference standard (molecular formula C10H8N2O2, MW 188.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C10H8N2O2, Perampanel Impurity 38 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 188.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Perampanel Impurity 38 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 2 |
Related Perampanel Standards
- Perampanel impurity 43 (CAS CATO-C4X-243043)
- Perampanel Impurity 17 (CAS 172732-52-4)
- Perampanel Impurity 16 (CAS 381233-78-9)
- Perampanel Impurity 14 (CAS 4341-02-0)
- Perampanel Impurity N1 (CAS 2377611-18-0)
- Perampanel Impurity 51 (CAS 943739-90-0)
- Perampanel Impurity 30 (CAS 1284376-94-8)
- Perampanel Impurity 35 (CAS CATO-C4X-243035)
Recommended Standards
- Arginine Impurity 17 (CAS 151512-14-0)
- Isosorbide Dinitrate Impurity 6 (CAS 65940-93-4)
- 3-Methyl-Quinoxaline-2-Carboxylic Acid (CAS 74003-63-7)
- Isosorbide Dinitrate Impurity 5 (CAS 13042-39-2)
- Betamethasone Impurity 75 (CAS CATO-C4X-143775)
- Paricalcitol Impurity 27 (CAS 139356-35-7)
- Ibrutinib Impurity 122 (CAS CATO-C4X-1064122)
- Benzyl-d7-amine HCl (CAS 352431-27-7)
- Methyl 2-[4-(methylsulfanyl)phenyl]benzoate (CAS 1820703-66-9)
- 1-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]-4-(4-methoxyphenyl)-1H-pyrazol-5-amine (CAS 955964-74-6)
- 5-Methyl-2-phenylbenzo[b]thiophene (CAS 55164-43-7)
- (4-Fluorobicyclo[2.2.1]heptan-1-yl)methyl 4-methylbenzenesulfonate (CAS 88888-32-8)
- 2-((4-(Ethoxycarbonyl)phenyl)amino)nicotinic acid (CAS 16344-34-6)
- 59880-97-6 Chemotactic peptide F-Met-Leu-Phe L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- N-Formyl-L-methionyl-L-leucyl-L-phenylalanine N-Formyl-Met-Leu-Phe N-Formylmethionine leucyl-phenylalanine fMLF fMLP (misnomer but widely used) (CAS 59880-97-6)
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