Perampanel Impurity 51 CAS 943739-90-0
| CAS No. | 943739-90-0 |
| Molecular Formula | C10H13BO4 |
| Molecular Weight | 208.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Perampanel Impurity 51 (CAS 943739-90-0, C10H13BO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Perampanel Impurity 51 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 208.02 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Perampanel Impurity 51 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13BO4 |
| Molecular Weight | 208.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
Related Perampanel Standards
- Perampanel Impurity N1 (CAS 2377611-18-0)
- Perampanel Impurity 14 (CAS 4341-02-0)
- Perampanel Impurity 38 (CAS 142929-10-0)
- Perampanel impurity 43 (CAS CATO-C4X-243043)
- Perampanel Impurity 17 (CAS 172732-52-4)
- Perampanel Impurity 30 (CAS 1284376-94-8)
- Perampanel Impurity 16 (CAS 381233-78-9)
- Perampanel Impurity 35 (CAS CATO-C4X-243035)
Recommended Standards
- 3-(iso-Propoxycarbonyl)phenylboronic acid 3-(isopropoxycarbonyl)benzeneboronic acid 3-(isopropoxycarbonyl)phenylboronic acid 3-(isopropylcarbonyl)phenylboronic acid 3-isopropoxycarbonylphenylboronic acid 342002-80-6 m-(isopropoxycarbonyl)phenylboronic acid propan-2-yl 3-(dihydroxyboranyl)benzoate (CAS 342002-80-6)
- 5-Bromothiazole-4-carboxylic Acid (CAS 103878-58-6)
- 4-Carboxy-3-isopropylphenylboronic acid (CAS 851335-14-3)
- (2-(Piperazin-1-yl)pyrimidin-5-yl)boronic acid (CAS 1176001-52-7)
- Finasteride Impurity 51 (CAS CATO-C4X-164551)
- FCN437 Impurity 1 (CAS 1665-65-2)
- Salicylic Acid Impurity 26 (CAS 2100-31-4)
- 2-Methyl-3-(prop-2-yn-1-yloxy)phenol (CAS 1094247-71-8)
- 2-(4-fluorophenyl) thiophene (CAS 58861-48-6)
- <I>N</I>-(3-butynyl)phthalimide (CAS 14396-90-8)
- 5,6-dihydroxybicyclo[2.2.1]hept-2-yl acetate (CAS 254112-21-5)
- 1-(cinnamylsulfinyl)-4-methylbenzene (CAS 911820-12-7)
- N-(azetidin-3-yl)cyclobutanecarboxamide hydrochloride (CAS 1803582-30-0)
- Semaglutide impurity 78 (CAS CATO-C4X-222678)
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