Perampanel Impurity N1 CAS 2377611-18-0
| CAS No. | 2377611-18-0 |
| Molecular Formula | C10H12BNO3 |
| Molecular Weight | 205.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Perampanel Impurity N1 (CAS 2377611-18-0) is a certified pharmaceutical impurity reference standard with the molecular formula C10H12BNO3 and a molecular weight of 205.02 g/mol.
Structurally, Perampanel Impurity N1 (C10H12BNO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.5, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 205.02 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Perampanel Impurity N1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12BNO3 |
| Molecular Weight | 205.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 1 |
Related Perampanel Standards
- Perampanel Impurity 14 (CAS 4341-02-0)
- Perampanel Impurity 51 (CAS 943739-90-0)
- Perampanel Impurity 38 (CAS 142929-10-0)
- Perampanel impurity 43 (CAS CATO-C4X-243043)
- Perampanel Impurity 17 (CAS 172732-52-4)
- Perampanel Impurity 30 (CAS 1284376-94-8)
- Perampanel Impurity 16 (CAS 381233-78-9)
- Perampanel Impurity 35 (CAS CATO-C4X-243035)
Recommended Standards
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- Omeprazole impurity 34 (CAS CATO-C4X-125534)
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- Bumetanide Impurity 52 (CAS CATO-C4X-198652)
- 2-chloro-N-[1-(2-oxo-2,3-dihydro-1H-indol-5-yl)ethyl]acetamide (CAS 1311313-81-1)
- 7-(4-Methoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine-3,8(2H,7H)-dione (CAS 1031577-95-3)
- 2-[methyl(propan-2-yl)amino]benzaldehyde (CAS 1021239-93-9)
- 1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one o-acetyloxime (CAS 67780-96-5)
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