4-Chloro-3-(hydroxymethyl)phenylboronic acid CAS 1430237-54-9
| CAS No. | 1430237-54-9 |
| Molecular Formula | C7H8BClO3 |
| Molecular Weight | 186.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-Chloro-3-(hydroxymethyl)phenylboronic acid (CAS 1430237-54-9), a certified reference material (molecular formula C7H8BClO3, MW 186.40 g/mol) for analytical method development and quality control.
The molecular framework of 4-Chloro-3-(hydroxymethyl)phenylboronic acid (C7H8BClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 4-Chloro-3-(hydroxymethyl)phenylboronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H8BClO3 |
| Molecular Weight | 186.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 2-Chloro-5-(hydroxymethyl)phenylboronic Acid (CAS 1003042-59-8)
- 3-Chloro-4-(hydroxymethyl)phenylboronic Acid (CAS 1190875-60-5)
- 4-Chloro-2-hydroxy-6-methylphenylboronic acid (CAS 1207961-50-9)
- (4-Chloro-2-(hydroxymethyl)phenyl)boronic acid (CAS 1365244-07-0)
- 3-Chloro-2-hydroxymethylphenylboronic acid (CAS 1451393-57-9)
- 3-Chloro-4-methoxyphenylboronic Acid (CAS 175883-60-0)
- 3-Chloro-2-methoxyphenylboronic Acid (CAS 179898-50-1)
- (2-Chloro-4-ethylpyrimidin-5-yl)boronic acid (CAS 2225177-41-1)
Recommended Standards
- Bis(trimethylsilyl)carbodiimide (CAS 1000-70-0)
- (2-Chloro-6-(hydroxymethyl)phenyl)boronic acid (CAS 2375070-88-3)
- Cyclopropyl zinc bromide solution (CAS 126403-68-7)
- (3-Chloro-4-hydroxy-2-methylphenyl)boronic acid (CAS 2280987-26-8)
- rac 2-Myristoyl-3-chloropropanediol, 95% (CAS 1330166-18-1)
- Methyl 2-((4-nitrobenzyl)oxy)benzoate (CAS 52803-89-1)
- 4-Chloro-n1-cyclohexylbenzene-1,2-diamine (CAS 169117-71-9)
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- 5-Chloro-4-isobutoxythiophene-2-carboxylic acid (CAS 1707568-63-5)
- Methyl 2,2-dimethyl-3-phenylpropanoate (CAS 14248-22-7)
- 1-(tert-Butoxycarbonyl)-4,4-dimethylpiperidine-3-carboxylic acid (CAS 1798843-57-8)
- 2-(2-Chlorophenoxy)propanehydrazide (CAS 52094-94-7)
- Methyl 3-(4-isopropylphenyl)-3-(1H-pyrrol-1-yl)propanoate (CAS 477850-23-0)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com