3-Chloro-2-hydroxymethylphenylboronic acid CAS 1451393-57-9
| CAS No. | 1451393-57-9 |
| Molecular Formula | C7H8BClO3 |
| Molecular Weight | 186.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Chloro-2-hydroxymethylphenylboronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-Chloro-2-hydroxymethylphenylboronic acid (CAS 1451393-57-9), a certified reference material (molecular formula C7H8BClO3, MW 186.40 g/mol) for analytical method development and quality control.
The molecular framework of 3-Chloro-2-hydroxymethylphenylboronic acid (C7H8BClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Chloro-2-hydroxymethylphenylboronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H8BClO3 |
| Molecular Weight | 186.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 2-Chloro-5-(hydroxymethyl)phenylboronic Acid (CAS 1003042-59-8)
- 3-Chloro-4-(hydroxymethyl)phenylboronic Acid (CAS 1190875-60-5)
- 4-Chloro-2-hydroxy-6-methylphenylboronic acid (CAS 1207961-50-9)
- (4-Chloro-2-(hydroxymethyl)phenyl)boronic acid (CAS 1365244-07-0)
- 4-Chloro-3-(hydroxymethyl)phenylboronic acid (CAS 1430237-54-9)
- 3-Chloro-4-methoxyphenylboronic Acid (CAS 175883-60-0)
- 3-Chloro-2-methoxyphenylboronic Acid (CAS 179898-50-1)
- (2-Chloro-4-ethylpyrimidin-5-yl)boronic acid (CAS 2225177-41-1)
Recommended Standards
- (2-Chloro-6-(hydroxymethyl)phenyl)boronic acid (CAS 2375070-88-3)
- (3-Chloro-4-hydroxy-2-methylphenyl)boronic acid (CAS 2280987-26-8)
- Bis(trimethylsilyl)carbodiimide (CAS 1000-70-0)
- (3-Chloro-5-(hydroxymethyl)phenyl)boronic acid (CAS 2121512-87-4)
- 2-Cyano-5-methyl-2-(3-methylbut-2-en-1-yl)hex-4-enoic acid (CAS 189640-37-7)
- (2S,4R)-4-(benzyloxy)-1-((benzyloxy)carbonyl)pyrrolidine-2-carboxylic acid (CAS 73004-31-6)
- Methyl 2-amino-2-(quinolin-6-yl)acetate (CAS 762219-22-7)
- 1-Phenyl-2-nitroethene (CAS 102-96-5)
- Iopamidol Impurity 52 (CAS 60166-91-8)
- 4-{[(2-furylmethyl)amino]methyl}-N-methylbenzamide hydrochloride (CAS 1171752-03-6)
- 3-[(Cyanomethyl)sulfanyl]-1-(2-methylphenyl)-5H,6H,7H-cyclopenta[c]pyridine-4-carbonitrile (CAS 439096-75-0)
- Alogliptin Impurity 8 (CAS 1820685-30-0)
- Ethyl 2-chloro-5-fluorobenzoate (CAS 57381-63-2)
- 59880-97-6 Chemotactic peptide F-Met-Leu-Phe L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- N-Formyl-L-methionyl-L-leucyl-L-phenylalanine N-Formyl-Met-Leu-Phe N-Formylmethionine leucyl-phenylalanine fMLF fMLP (misnomer but widely used) (CAS 59880-97-6)
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