3-Chloro-4-methoxyphenylboronic Acid CAS 175883-60-0
| CAS No. | 175883-60-0 |
| Molecular Formula | C7H8BClO3 |
| Molecular Weight | 186.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Chloro-4-methoxyphenylboronic Acid.
3-Chloro-4-methoxyphenylboronic Acid (CAS 175883-60-0), molecular formula C7H8BClO3 and molecular weight 186.40 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Chloro-4-methoxyphenylboronic Acid (C7H8BClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Chloro-4-methoxyphenylboronic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8BClO3 |
| Molecular Weight | 186.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 2-Chloro-5-(hydroxymethyl)phenylboronic Acid (CAS 1003042-59-8)
- 3-Chloro-4-(hydroxymethyl)phenylboronic Acid (CAS 1190875-60-5)
- 4-Chloro-2-hydroxy-6-methylphenylboronic acid (CAS 1207961-50-9)
- (4-Chloro-2-(hydroxymethyl)phenyl)boronic acid (CAS 1365244-07-0)
- 4-Chloro-3-(hydroxymethyl)phenylboronic acid (CAS 1430237-54-9)
- 3-Chloro-2-hydroxymethylphenylboronic acid (CAS 1451393-57-9)
- 3-Chloro-2-methoxyphenylboronic Acid (CAS 179898-50-1)
- (2-Chloro-4-ethylpyrimidin-5-yl)boronic acid (CAS 2225177-41-1)
Recommended Standards
- (2-Chloro-6-(hydroxymethyl)phenyl)boronic acid (CAS 2375070-88-3)
- (3-Chloro-4-hydroxy-2-methylphenyl)boronic acid (CAS 2280987-26-8)
- (3-Chloro-5-(hydroxymethyl)phenyl)boronic acid (CAS 2121512-87-4)
- (4-Chloro-2-ethylpyrimidin-5-yl)boronic acid (CAS 2225169-99-1)
- 1-(5-Hydroxy-4-methyltetrahydrofuran-3-yl)ethanone (CAS 113531-94-5)
- 4-Oxothiochroman-7-yl trifluoromethanesulfonate (CAS 2768536-01-0)
- Methyl 2-(4-benzoylphenoxy)acetate (CAS 57682-09-4)
- 2-Chloro-3-iodopyrazine (CAS 191340-85-9)
- 4,6-Dihydroxybenzo[d]thiazole-2-carbonitrile (CAS 7267-41-6)
- 5-(Benzenesulfonyl)-4-[(4-fluorophenyl)sulfanyl]-2-phenylpyrimidine (CAS 478081-01-5)
- 1-(3-Fluorobenzyl)imidazolidin-2-one (CAS 60927-96-0)
- 5,8-Methanonaphtho[2,3-c]furan-1,3(5H,8H)-dione (CAS 137495-56-8)
- 6-(Aminomethyl)uracil (CAS 20989-02-0)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
Why CATO?
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