Netupitant Impurity 1 CAS 1431216-62-4
| CAS No. | 1431216-62-4 |
| Molecular Formula | C30H32F6N4O2 |
| Molecular Weight | 594.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Netupitant Impurity 1 (CAS 1431216-62-4), a pharmacopoeial impurity reference standard (molecular formula C30H32F6N4O2, MW 594.59 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C30H32F6N4O2, Netupitant Impurity 1 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 594.59 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Netupitant Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C30H32F6N4O2 |
| Molecular Weight | 594.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Netupitant Standards
- Netupitant Impurity N1 (CAS 910808-12-7)
- Netupitant N-Oxide (CAS 910808-11-6)
- Netupitant Impurity 39 (CAS CATO-C4X-122339)
- Netupitant Impurity 48 (CAS CATO-C4X-122348)
- Netupitant Impurity 53 (CAS CATO-C4X-122353)
- Netupitant-d6 (CAS 2070015-31-3)
- Netupitant Impurity 27 (CAS 2920686-87-7)
- Netupitant Impurity 54 (CAS CATO-C4X-122354)
Recommended Standards
- Rivaroxaban Impurity 216 (CAS CATO-C4X-1090216)
- Ceftiolene (CAS 77360-52-2)
- Barium calcium tungsten oxide 99.9% trace metals basis (CAS 15552-14-4)
- Pseudolaric acid B-glucopyranoside (CAS 98891-41-9)
- Aspirin impurity 30 (CAS 85531-18-6)
- Nafamostat Impurity 14 (CAS 62529-01-5)
- Ketotifen Impurity 34 (CAS CATO-C4X-204634)
- N-((1H-Benzo[d]imidazol-2-yl)methyl)-2-(furan-2-carboxamido)oxazole-4-carboxamide (CAS 1286712-61-5)
- 4-(2-((2-(4-Nitrophenyl)benzo[d]imidazo[2,1-b]thiazol-7-yl)oxy)ethyl)morpholine (CAS 950769-60-5)
- 2-((3-Methoxypropyl)amino)nicotinonitrile (CAS 945298-39-5)
- 2-(2-Cyanophenyl)-4-trifluoromethylacetophenone (CAS 898784-49-1)
- 1-((2-Fluorophenyl)sulfonyl)-5-(3-methylbenzo[b]thiophen-2-yl)-1H-pyrazole (CAS 956782-89-1)
- (Z)-2-Oleamidoethyl dihydrogen phosphate (CAS 24435-25-4)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com