Gemcitabine impurity 22 CAS 143234-90-6
| CAS No. | 143234-90-6 |
| Molecular Formula | C17H20F2O6 |
| Molecular Weight | 358.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Gemcitabine impurity 22 (CAS 143234-90-6), a pharmacopoeial impurity reference standard (molecular formula C17H20F2O6, MW 358.33 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C17H20F2O6, Gemcitabine impurity 22 contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 358.33 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Gemcitabine impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H20F2O6 |
| Molecular Weight | 358.33 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
Related Gemcitabine Standards
- Gemcitabine Impurity 31 (CAS 142816-70-4)
- Gemcitabine Impurity 5 (CAS 2174019-90-8)
- Gemcitabine Impurity N19 (CAS 1147182-15-7)
- Gemcitabine Impurity 18 (CAS 139729-89-8)
- Gemcitabine Monophosphate (CAS 116371-67-6)
- Gemcitabine Impurity 10 (CAS 1217452-91-9)
- Gemcitabine Impurity 17 (CAS 197452-15-6)
- Gemcitabine Impurity 29 (CAS 122111-02-8)
Recommended Standards
- N-benzyl-2-(pyridin-2-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamide (CAS 865660-42-0)
- 143234-92-8 2-Deoxy-2,2-difluoro-4,5-O-(1-methylethylidene)-D-threo-pentonic Acid Ethyl Ester Benzoate 2-Deoxy-2,2-difluoro-4,5-O-isopropylidene-D-threo-pentonic Acid Ethyl Ester Benzoate (CAS 143234-92-8)
- N-[(E)-(3-Phenyl-1H-pyrazol-4-yl)methylidene]-4-(trifluoromethyl)benzenecarbohydrazide (CAS 477710-90-0)
- 4-Ethynyl-1-((4-nitrophenyl)sulfonyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one (CAS 2097770-05-1)
- Meropenem Impurity 43 (CAS 96035-15-3)
- Empagliflozin impurity 212 (CAS CATO-C4X-1065212)
- Abiraterone Impurity 36 (CAS CATO-C4X-107036)
- 1-tert-Butyl 3-methyl 4-aminopyrrolidine-1,3-dicarboxylate (CAS 362491-96-1)
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(4-hydroxyphenyl)acetonitrile (CAS 321432-72-8)
- Sodium (E)-5-(2-carbamoylhydrazono)-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indole-2-sulfonate (CAS 942433-41-2)
- 8-Chloro-1H-pyrazolo[4,3-c]quinolin-3(2H)-one (CAS 1015605-31-8)
- Sofosbuvir Impurity 25 (CAS CATO-C4X-105225)
- Disperse Red 17 (CAS 3179-89-3)
- Tirzepatide Impurity 38 (CAS CATO-C4X-324038)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com