Gemcitabine Impurity N19 CAS 1147182-15-7
| CAS No. | 1147182-15-7 |
| Molecular Formula | C16H15F2N3O5 |
| Molecular Weight | 367.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 367.30 g/mol gives Gemcitabine Impurity N19 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Gemcitabine Impurity N19 (CAS 1147182-15-7), a pharmacopoeial impurity reference standard (molecular formula C16H15F2N3O5, MW 367.30 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Gemcitabine Impurity N19 (C16H15F2N3O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Gemcitabine Impurity N19 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H15F2N3O5 |
| Molecular Weight | 367.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Gemcitabine Standards
- Gemcitabine Impurity 31 (CAS 142816-70-4)
- Gemcitabine Impurity 5 (CAS 2174019-90-8)
- Gemcitabine impurity 22 (CAS 143234-90-6)
- Gemcitabine Impurity 10 (CAS 1217452-91-9)
- Gemcitabine Impurity 17 (CAS 197452-15-6)
- Gemcitabine Impurity 29 (CAS 122111-02-8)
- Gemcitabine Impurity 32 (CAS 122111-01-7)
- Gemcitabine Impurity 16 (CAS 1173824-58-2)
Recommended Standards
- 4-(((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)-4-oxobutanoic Acid (CAS 102029-71-0)
- [(2R,3S,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-methoxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate (CAS 73646-17-0)
- (2R,3R,4R,5R)-4-(((2S,3R,4S,5S,6R)-6-(azidomethyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal (CAS 1499187-31-3)
- (4-(Methylselanyl)phenyl)(3,4,5-trimethoxyphenyl)methanol (CAS 2123478-18-0)
- Ornidazole Impurity 102 (CAS CATO-C4X-1331102)
- N-Nitroso Nafamostat impurity 119 (CAS CATO-C4X-1332119)
- Eperisone Impurity 46 HCl (CAS CATO-C4X-227946)
- 2-((2-((4-Fluorobenzyl)amino)-2-oxoethyl)thio)acetic acid (CAS 338794-24-4)
- 4,4'-(Diazene-1,2-diyl)dibenzaldehyde (CAS 140661-40-1)
- Ethyl 4-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)butanoate (CAS 64462-87-9)
- Oseltamivir Impurity 164 (CAS 204255-02-7)
- 5-(Methylsulfonyl)quinolin-3-amine (CAS 1956341-17-5)
- Afatinib Impurity 16 (CAS CATO-C4X-100616)
- Biotinyl-S6 Phosphate Acceptor Peptide trifluoroacetate salt (CAS 1815618-12-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com