Irinotecan Lactone Impurity CAS 143490-53-3
| CAS No. | 143490-53-3 |
| Molecular Formula | C32H36N4O5 |
| Molecular Weight | 556.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Irinotecan Lactone Impurity (CAS 143490-53-3), a pharmacopoeial impurity reference standard (molecular formula C32H36N4O5, MW 556.65 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Irinotecan Lactone Impurity is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 556.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Irinotecan Lactone Impurity under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C32H36N4O5 |
| Molecular Weight | 556.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 4 |
Related Irinotecan Standards
- Irinotecan Impurity 29 (CAS CATO-C4X-166729)
- Irinotecan EP Impurity A (CAS 103816-16-6)
- Irinotecan Impurity 38 (CAS 143490-54-4)
- Irinotecan Impurity 28 (CAS CATO-C4X-166728)
- Irinotecan Impurity 69 (CAS 100286-92-8)
- Irinotecan Impurity 51 (CAS 2944102-98-9)
- Irinotecan Impurity 34 (CAS 176515-52-9)
- Irinotecan Impurity 30 (CAS CATO-C4X-166730)
Recommended Standards
- Carvedilol Impurity 34 (CAS 1059573-45-3)
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- Ibrutinib Impurity 71 (CAS CATO-C4X-106471)
- Oxacillin Impurity 33 (CAS 5053-35-0（free base）)
- Tirofiban Impurity 45 (CAS 3728-20-9)
- (2-Ethoxyphenyl)(2-((3-methylbenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone (CAS 851803-26-4)
- n-(4-Bromo-3-methylphenyl)tetrahydro-2h-pyran-4-amine (CAS 1154889-42-5)
- 1-((Phenylthio)methyl)cyclopentan-1-ol (CAS 101704-18-1)
- 1-(3-Chloro-4-hydroxyphenyl)propan-2-one (CAS 84023-32-5)
- 2,7-Dithiaoctane (CAS 15394-33-9)
- 6-(4-Fluorophenyl)pyrimidine-4-carboxylic acid (CAS 887407-77-4)
- Des-Ala21-Tirzepatide (CAS CATO-CPTD788952)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com