Irinotecan Impurity 51 CAS 2944102-98-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.2944102-98-9
Molecular FormulaC33H33N3O6
Molecular Weight567.63 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Irinotecan Impurity 51 CAS 2944102-98-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 567.63 g/mol gives Irinotecan Impurity 51 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Irinotecan Impurity 51 (CAS 2944102-98-9), a pharmacopoeial impurity reference standard (molecular formula C33H33N3O6, MW 567.63 g/mol) used for the identification and quantification of trace impurities in APIs.

Irinotecan Impurity 51 (C33H33N3O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Irinotecan Impurity 51 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC33H33N3O6
Molecular Weight567.63 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)19.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2004
Nitrogen Atoms3

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