Duloxetine-d3 HCl CAS 1435727-97-1
| CAS No. | 1435727-97-1 |
| Molecular Formula | - |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 336.89 g/mol gives Duloxetine-d3 HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Duloxetine-d3 HCl (CAS 1435727-97-1), molecular formula C18H16D3NOSHCl and molecular weight 336.89 g/mol, is a CATO reference standard with documented purity and traceability.
Duloxetine-d3 HCl (C18H16D3NOSHCl) contains deuterium isotope labeling, a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Duloxetine-d3 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16D3NOS HCl |
| Molecular Weight | 336.89 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Duloxetine Standards
- Duloxetine EP Impurity E HCl (CAS 1033719-36-6)
- Duloxetine EP Impurity E (CAS 1033803-59-6)
- Duloxetine Impurity 55 (CAS 1045348-04-6)
- Duloxetine Impurity 9 (CAS 110-14-5)
- rac-Duloxetine EP Impurity F HCl (CAS 1104890-90-5)
- Duloxetine EP Impurity B (CAS 116539-55-0)
- Duloxetine Impurity (CAS 116539-57-2)
- Duloxetine (CAS 116539-59-4)
Recommended Standards
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