3-Chloro-7-fluoro-5-nitro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide CAS 1437481-62-3
| CAS No. | 1437481-62-3 |
| Molecular Formula | C7H3ClFN3O4S |
| Molecular Weight | 279.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 3-Chloro-7-fluoro-5-nitro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 279.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-Chloro-7-fluoro-5-nitro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 1437481-62-3), molecular formula C7H3ClFN3O4S and molecular weight 279.63 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chloro-7-fluoro-5-nitro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3ClFN3O4S |
| Molecular Weight | 279.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-Chloro-5-fluoro-7-nitro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 1437458-04-2)
- 5-Chloro-2-((5-nitrofuran-2-yl)oxy)benzofuran (CAS 89266-67-1)
- 2-[3-chloro-5-methoxy-4-(2,2,2-trifluoroethoxy)phenyl]acetonitrile (CAS 1209937-54-1)
- 3-(4-Chloro-2-fluoro-5-methylphenyl)-5-(trifluoromethyl)isoxazole (CAS 653569-92-7)
- 8-Chloro-5-fluoro-4-methoxy-2-(trifluoromethyl)quinoline (CAS 917251-95-7)
- n-[2-chloro-5-(trifluoromethyl)phenyl]-3-oxobutanamide (CAS 585-97-7)
- N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide (CAS 392721-37-8)
- (Z)-3-Chloro-N'-hydroxy-N-(prop-2-en-1-yl)-5-(trifluoromethyl)pyridine-2-carboximidamide (CAS 1273562-44-9)
Recommended Standards
- (4-Bromo-2-chlorophenoxy)trimethylsilane (CAS 809278-96-4)
- 5-(Chloromethyl)-3-(4-fluoro-2-(trifluoromethyl)phenyl)isoxazole (CAS 858939-35-2)
- Eltrombopag impurity 139 (CAS CATO-C4X-1198139)
- 3-Phenyl-3-[(2,2,2-trifluoroacetyl)amino]propanoyl chloride (CAS 117291-26-6)
- 5-Chloro-6-hydroxypicolinic acid (CAS 1822931-95-2)
- 2-Chloro-2-(4-chlorophenyl)-1H-indene-1,3(2H)-dione (CAS 730-74-5)
- n-[1-(3-fluoro-4-methoxyphenyl)ethyl]sulfamide (CAS 1280985-10-5)
- Methyl 3,3,3-trifluoro-2-hydroxy-2-methylpropanoate (CAS 337-16-6)
- Sertindole Impurity 1 (CAS 138900-22-8)
- 2-chloro-N-[2-(1H-indol-3-yl)-2-(4-methoxyphenyl)ethyl]acetamide (CAS 924219-40-9)
- 6-O-(b-D-Galactopyranosyl)-D-glucopyranose (CAS 28447-39-4)
- 5-Benzyl-5-azaspiro[3.5]nonan-8-amine (CAS 2361644-19-9)
- 3,5-dichloro-N-methyl-N-[3-(trifluoromethyl)phenyl]benzenecarboxamide 478042-64-7 KS-0000377B (CAS 478042-64-7)
- Semaglutide impurity 236 (CAS CATO-C4X-2226236)
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