Palbociclib Impurity 45 CAS 1439-36-7

Description

Compared with other compounds in its class, the molecular weight of 318.35 g/mol gives Palbociclib Impurity 45 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Palbociclib Impurity 45 (CAS 1439-36-7) is a certified pharmaceutical impurity reference standard with the molecular formula C21H19OP and a molecular weight of 318.35 g/mol.

Based on its molecular formula C21H19OP, Palbociclib Impurity 45 contains a steroid core, organophosphorus functionality, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 318.35 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Palbociclib Impurity 45 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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