Progesterone Impurity 86 CAS 143955-73-1
| CAS No. | 143955-73-1 |
| Molecular Formula | C23H32O3 |
| Molecular Weight | 356.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Progesterone Impurity 86 (CAS 143955-73-1) is a certified pharmaceutical impurity reference standard with the molecular formula C23H32O3 and a molecular weight of 356.50 g/mol.
Progesterone Impurity 86 (C23H32O3) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Progesterone Impurity 86 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H32O3 |
| Molecular Weight | 356.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
Related Progesterone Standards
- Progesterone EP Impurity D (CAS 5035-09-6)
- Progesterone EP Impurity E (CAS 5062-62-4)
- Progesterone Impurity 82 (CAS 63088-24-4)
- Progesterone Impurity 92 (CAS CATO-C4X-150292)
- Progesterone Impurity N4 (CAS 2453-93-2)
- Progesterone Impurity 47 (CAS CATO-C4X-150247)
- Progesterone Impurity 62 (CAS 87421-42-9)
- Progesterone Impurity 66 (CAS CATO-C4X-150266)
Recommended Standards
- Palonosetron Impurity 49 (CAS CATO-C4X-110549)
- Prostaglandin F1alpha (CAS 745-62-0)
- Palonosetron Impurity 45 (CAS CATO-C4X-110545)
- Altrenogest impurity 17 (CAS 32259-88-4)
- (S,S)-Moxifloxacin Impurity 97 (CAS CATO-C4X-107497)
- Edoxaban Impurity N37 (CAS 365997-34-8)
- Doxepin EP Impurity B (CAS 4504-88-5)
- 2,2-Difluoro-1-(4-phenoxyphenyl)ethanone (CAS 1352222-93-5)
- N-(2-methoxypyridin-3-yl)pivalamide (CAS 125867-19-8)
- N1-Cyclopropyl-N1-((3-methylthiophen-2-yl)methyl)ethane-1,2-diamine (CAS 1353952-28-9)
- (S)-3-(4-(borono-10B)phenyl)-2-formamidopropanoic acid (CAS CATO-C3D-263183)
- 2-(1-(3-Fluorophenyl)-1h-1,2,3-triazol-4-yl)propan-2-ol (CAS 924859-06-3)
- 5-Chloro-3-(3,5-difluorophenyl)-1,2,4-thiadiazole (CAS 1491356-45-6)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
Why CATO?
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