Progesterone Impurity 62 CAS 87421-42-9
| CAS No. | 87421-42-9 |
| Molecular Formula | C22H34O3 |
| Molecular Weight | 346.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, a hydroxyl group, an ether linkage, Progesterone Impurity 62 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 346.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a process- or degradation-related impurity, Progesterone Impurity 62 (CAS 87421-42-9, C22H34O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Progesterone Impurity 62 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H34O3 |
| Molecular Weight | 346.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
Related Progesterone Standards
- Progesterone Impurity 66 (CAS CATO-C4X-150266)
- Progesterone Impurity 67 (CAS CATO-C4X-150267)
- Progesterone Impurity N3 (CAS 5327-60-6)
- Progesterone Impurity 46 (CAS CATO-C4X-150246)
- Progesterone Impurity 52 (CAS 14508-05-5)
- Progesterone Impurity 65 (CAS CATO-C4X-150265)
- Progesterone Impurity 69 (CAS CATO-C4X-150269)
- Progesterone Impurity 81 (CAS CATO-C4X-150281)
Recommended Standards
- Budesonide Impurity 64 (CAS 69155-84-6)
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- Treprostinil Impurity 2 (CAS CATO-C4X-21162)
- Betamethasone Impurity 27 (CAS 116846-77-6)
- Methotrexate Hydrate EP Impurity B (CAS 1217459-90-9)
- Celecoxib Impurity 48 (CAS 921617-76-7)
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