Trazodone Impurity 29 CAS 2727463-29-6
| CAS No. | 2727463-29-6 |
| Molecular Formula | C40H46Cl2N10O2 |
| Molecular Weight | 769.77 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Trazodone Impurity 29 (CAS 2727463-29-6) is a certified pharmaceutical impurity reference standard with the molecular formula C40H46Cl2N10O2 and a molecular weight of 769.77 g/mol.
Trazodone Impurity 29 (C40H46Cl2N10O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Trazodone Impurity 29 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C40H46Cl2N10O2 |
| Molecular Weight | 769.77 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 10 |
Related Trazodone Standards
- Trazodone impurity 42 (CAS CATO-C4X-177242)
- Trazodone impurity 56 (CAS CATO-C4X-177256)
- Trazodone Impurity 94 (CAS CATO-C4X-177294)
- Trazodone Impurity 75 (CAS CATO-C4X-177275)
- Trazodone Impurity 83 (CAS CATO-C4X-177283)
- Trazodone Impurity 86 (CAS CATO-C4X-177286)
- Trazodone Impurity 104 (CAS CATO-C4X-1772104)
- Trazodone Impurity 105 (CAS CATO-C4X-1772105)
Recommended Standards
- 3-Bromo-N,N-diethylaniline (CAS 53142-19-1)
- Fluo-3 (CAS 123632-39-3)
- N1,N1-Dihexadecyl-N4-(3-(triethoxysilyl)propyl)succinamide (CAS 244096-38-6)
- Rifamycin impurity 19 (CAS 15271-73-5)
- Darolutamide Impurity 1 (CAS CATO-C4X-31061)
- Flurbiprofen Impurity 16 (CAS 52807-12-2)
- Nifuratel Impurity 22 (CAS CATO-C4X-127222)
- (2-Bromopyrimidin-5-yl)methanamine (CAS 1780419-54-6)
- Cyclopropyl diphenyl carbinol (CAS 5785-66-0)
- 22-alpha-Hydroxy Cholesterol (CAS 17954-98-2)
- (R)-Benzyl 2-methyl-3-oxopiperazine-1-carboxylate (CAS 1373232-19-9)
- 1-(6-(2,4-Dichlorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)-2-methylpropan-1-amine (CAS 1706432-98-5)
- (R)-tert-Butyl 1-(3-fluorobenzoyl)pyrrolidin-3-ylcarbamate (CAS 1286208-20-5)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
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