Ethyl 3-(2-chloro-5-(trifluoromethyl)phenoxy)propanoate CAS 1443303-84-1
| CAS No. | 1443303-84-1 |
| Molecular Formula | C12H12ClF3O3 |
| Molecular Weight | 296.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Ethyl 3-(2-chloro-5-(trifluoromethyl)phenoxy)propanoate (CAS 1443303-84-1), a certified reference material (molecular formula C12H12ClF3O3, MW 296.67 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, Ethyl 3-(2-chloro-5-(trifluoromethyl)phenoxy)propanoate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 296.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12ClF3O3 |
| Molecular Weight | 296.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
Related Ethyl Standards
- Ethyl 2-(4-chloro-5-cyclopropyl-3-(trifluoromethyl)-1h-pyrazol-1-yl)acetate (CAS 1002033-65-9)
- Methyl 3-(4-chloro-5-cyclopropyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)propanoate (CAS 1005583-79-8)
- Methyl 2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)-2-methylpropanoate (CAS 1354448-69-3)
- (2-Chloro-6-trifluoromethyl-pyridin-4-yl)-carbamic acid tert-butyl ester (CAS 1373223-18-7)
- 2-(2-(2-Chloro-4-(trifluoromethyl)phenoxy)ethyl)-1,3-dioxolane (CAS 1443303-07-8)
- 2-(2-(2-Chloro-5-(trifluoromethyl)phenoxy)ethyl)-1,3-dioxolane (CAS 1443303-77-2)
- Ethyl 3-(2-chloro-4-(trifluoromethyl)phenoxy)propanoate (CAS 1443345-65-0)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indole (CAS 151387-66-5)
Recommended Standards
- (S)-(-)-NBD-Pro-COCl [=(S)-(-)-4-Nitro-7-(2-chloroformylpyrrolidin-1-yl)-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for e.e. Determination] (CAS 159717-68-7)
- (R)-(+)-NBD-Pro-COCl [=(R)-(+)-4-Nitro-7-(2-chloroformylpyrrolidin-1-yl)-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for e.e. Determination] (CAS 159717-69-8)
- tert-Butyl (6-chloro-5-(trifluoromethyl)pyridin-3-yl)carbamate (CAS 1057383-91-1)
- 8-Chloro-3-phenyl-6-(trifluoromethyl)imidazo[1,5-a]pyridine (CAS 1781241-49-3)
- 2,4-Hexadienal(mixture of isomers) (CAS 80466-34-8)
- 1-Acetylazetidine-3-carbonitrile (CAS 2112395-13-6)
- 3-(Piperidin-4-ylmethoxy)pyridazine (CAS 1225227-37-1)
- 4-amino-N-methoxy-N-methylbenzenesulfonamide (CAS 33529-48-5)
- (S)-Methyl 2-amino-4-(dimethylamino)butanoate (CAS 794486-86-5)
- (1S,2S,4S)-N-Methylbicyclo[2.2.1]hept-5-ene-2-carboxamide (CAS 13295-40-4)
- 2-(4-bromophenoxy)-3-methylbutanenitrile (CAS 1803598-45-9)
- 8-nitro-2,3,4,5-tetrahydro-1,4-benzoxazepine (CAS 1085728-28-4)
- 1-(3-(2-Methoxyethyl)-1,2,4-oxadiazol-5-yl)-3-(methylthio)propan-1-amine oxalate (CAS 1820705-96-1)
- Neuropeptide Y, porcine (CAS 82785-45-3)
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