Ethyl 3-(2-chloro-4-(trifluoromethyl)phenoxy)propanoate CAS 1443345-65-0
| CAS No. | 1443345-65-0 |
| Molecular Formula | C12H12ClF3O3 |
| Molecular Weight | 296.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 296.67 g/mol gives Ethyl 3-(2-chloro-4-(trifluoromethyl)phenoxy)propanoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 3-(2-chloro-4-(trifluoromethyl)phenoxy)propanoate (CAS 1443345-65-0) is a high-purity analytical reference standard with the molecular formula C12H12ClF3O3 and a molecular weight of 296.67 g/mol.
Based on its molecular formula C12H12ClF3O3, Ethyl 3-(2-chloro-4-(trifluoromethyl)phenoxy)propanoate contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 296.67 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12ClF3O3 |
| Molecular Weight | 296.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
Related Ethyl Standards
- Ethyl 2-(4-chloro-5-cyclopropyl-3-(trifluoromethyl)-1h-pyrazol-1-yl)acetate (CAS 1002033-65-9)
- Methyl 3-(4-chloro-5-cyclopropyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)propanoate (CAS 1005583-79-8)
- Methyl 2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)-2-methylpropanoate (CAS 1354448-69-3)
- (2-Chloro-6-trifluoromethyl-pyridin-4-yl)-carbamic acid tert-butyl ester (CAS 1373223-18-7)
- 2-(2-(2-Chloro-4-(trifluoromethyl)phenoxy)ethyl)-1,3-dioxolane (CAS 1443303-07-8)
- 2-(2-(2-Chloro-5-(trifluoromethyl)phenoxy)ethyl)-1,3-dioxolane (CAS 1443303-77-2)
- Ethyl 3-(2-chloro-5-(trifluoromethyl)phenoxy)propanoate (CAS 1443303-84-1)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indole (CAS 151387-66-5)
Recommended Standards
- (S)-(-)-NBD-Pro-COCl [=(S)-(-)-4-Nitro-7-(2-chloroformylpyrrolidin-1-yl)-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for e.e. Determination] (CAS 159717-68-7)
- (R)-(+)-NBD-Pro-COCl [=(R)-(+)-4-Nitro-7-(2-chloroformylpyrrolidin-1-yl)-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for e.e. Determination] (CAS 159717-69-8)
- 8-Chloro-3-phenyl-6-(trifluoromethyl)imidazo[1,5-a]pyridine (CAS 1781241-49-3)
- tert-Butyl (2-chloro-5-(trifluoromethyl)pyridin-3-yl)carbamate (CAS 1820707-62-7)
- Cyclododecanone (CAS 830-13-7)
- 2-Chloro-4-methyl-1-(trifluoromethoxy)benzene (CAS 75462-60-1)
- 2-((2-Nitrophenyl)sulfonyl)-5-(trifluoromethyl)-1,3,4-thiadiazole (CAS 62617-19-0)
- N2-Cyclopentylpyridine-2,5-diamine trihydrochloride (CAS 1707584-11-9)
- 2-Amino-1-methyl-4,5-dihydro-1h-imidazole-4,5-dione, trifluoroacetic acid (CAS 1423031-23-5)
- (3-IODOPHENYL)METHANAMINE 3-IODOBENZYLAMINE 3-Iodobenzyl amine 696-40-2 AS02300 AURORA KA-7711 PHARMABRIDGE P-1639 RARECHEM AL BW 0705 (CAS 696-40-2)
- 7-Hydroxy-3-methylisoxazolo[4,5-b]pyridin-5(4H)-one (CAS 83988-34-5)
- 4-({[(4-chlorophenyl)methyl]sulfanyl}methyl)-6-[(4-chlorophenyl)sulfanyl]-2-(pyridin-2-yl)pyrimidine (CAS 338960-88-6)
- 2-Ethylhexyl octanoate (CAS 63321-70-0)
- (Glu9)-Exenatide (2-39) trifluoroacetate salt (CAS 196109-34-9)
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