4'-Bromo-4-fluoro-2-methyl-1,1'-biphenyl CAS 1443325-28-7
| CAS No. | 1443325-28-7 |
| Molecular Formula | C13H10BrF |
| Molecular Weight | 265.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4'-Bromo-4-fluoro-2-methyl-1,1'-biphenyl (CAS 1443325-28-7), molecular formula C13H10BrF and molecular weight 265.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4'-Bromo-4-fluoro-2-methyl-1,1'-biphenyl (C13H10BrF) is characterized by fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4'-Bromo-4-fluoro-2-methyl-1,1'-biphenyl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10BrF |
| Molecular Weight | 265.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 4-Bromo-2-methoxy-1-(methylsulfonyl)benzene (CAS 1095544-87-8)
- Methyl 4-bromo-3-methoxy-5-methyl-2-thiophenecarboxylate (CAS 123342-03-0)
- (3-Bromo-5-(methylsulfonyl)phenyl)methanol (CAS 1338796-07-8)
- 4'-Bromo-3-fluoro-4-methyl-1,1'-biphenyl (CAS 1443312-45-5)
- 3'-Bromo-3-fluoro-2-methyl-1,1'-biphenyl (CAS 1443313-42-5)
- 3'-Bromo-4-fluoro-2-methyl-1,1'-biphenyl (CAS 1443314-36-0)
- 4'-Bromo-5-fluoro-2-methyl-1,1'-biphenyl (CAS 1443325-46-9)
- 4'-Bromo-4-fluoro-3-methyl-1,1'-biphenyl (CAS 1443327-01-2)
Recommended Standards
- 1-(2-Bromoallyl)-4-fluoronaphthalene (CAS 1443326-72-4)
- N-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-acetamide (CAS 1346245-52-0)
- 3'-Bromo-3-fluoro-4-methyl-1,1'-biphenyl (CAS 1443327-15-8)
- 3'-Bromo-5-fluoro-2-methyl-1,1'-biphenyl (CAS 1443338-85-9)
- Calcium hexadecan-1-olate palmitate (CAS 542-42-7)
- (R)-2-(Ethylamino)butan-1-ol (CAS 83890-09-9)
- 1-((4-Cyclohexylphenyl)sulfonyl)-4-phenylpiperazine (CAS 430471-95-7)
- 2-((2,4-dimethylphenyl)amino)benzoic acid (CAS 27210-58-8)
- (3-Fluoro-4-(isopentyloxy)phenyl)methanol (CAS 1037139-62-0)
- Ethyl 3-bromoimidazo[1,2-a]pyrimidine-7-carboxylate (CAS 1251033-23-4)
- Methyl 2-bromo-6-methylisonicotinate (CAS 884494-71-7)
- Deoxynivalenol 15-Glucuronide (CAS 1372859-16-9)
- 3-Bromo-5-(m-tolyl)-1H-1,2,4-triazole (CAS 1227465-57-7)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
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