4'-Bromo-4-fluoro-3-methyl-1,1'-biphenyl CAS 1443327-01-2
| CAS No. | 1443327-01-2 |
| Molecular Formula | C13H10BrF |
| Molecular Weight | 265.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4'-Bromo-4-fluoro-3-methyl-1,1'-biphenyl (C13H10BrF) is characterized by fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4'-Bromo-4-fluoro-3-methyl-1,1'-biphenyl (CAS 1443327-01-2) is a high-purity analytical reference standard with the molecular formula C13H10BrF and a molecular weight of 265.12 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H10BrF |
| Molecular Weight | 265.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
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- 4'-Bromo-4-fluoro-2-methyl-1,1'-biphenyl (CAS 1443325-28-7)
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Recommended Standards
- 1-(2-Bromoallyl)-4-fluoronaphthalene (CAS 1443326-72-4)
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- 3'-Bromo-5-fluoro-2-methyl-1,1'-biphenyl (CAS 1443338-85-9)
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