Dapagliflozin Impurity N34 CAS 1443341-94-3

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.1443341-94-3
Molecular FormulaC27H31ClO9
Molecular Weight534.98 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Dapagliflozin Impurity N34 CAS 1443341-94-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 534.98 g/mol gives Dapagliflozin Impurity N34 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Dapagliflozin Impurity N34 (CAS 1443341-94-3) is a certified pharmaceutical impurity reference standard with the molecular formula C27H31ClO9 and a molecular weight of 534.98 g/mol.

Dapagliflozin Impurity N34 (C27H31ClO9) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC27H31ClO9
Molecular Weight534.98 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity>90%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentCl-containing

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