(4-Chloro-3-fluorophenyl)(cyclopropyl)methanol CAS 1443342-24-2
| CAS No. | 1443342-24-2 |
| Molecular Formula | C10H10ClFO |
| Molecular Weight | 200.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, (4-Chloro-3-fluorophenyl)(cyclopropyl)methanol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 200.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
(4-Chloro-3-fluorophenyl)(cyclopropyl)methanol (CAS 1443342-24-2), molecular formula C10H10ClFO and molecular weight 200.64 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10ClFO |
| Molecular Weight | 200.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-(2-Chloro-6-fluorophenyl)butan-2-one (CAS 1019769-64-2)
- 5-Chloro-3-fluoro-2-(pyrrolidin-1-yl)pyridine (CAS 1020253-18-2)
- 5-Chloro-2-thiobenzenesulfonyl fluoride (CAS 108158-05-0)
- 4-(2-Chloro-4-fluorophenyl)butan-2-one (CAS 1099621-26-7)
- 1-(2-Chloro-6-fluorophenyl)butan-2-one (CAS 1178854-65-3)
- (4-Chloro-2-fluorophenyl)(cyclopropyl)methanol (CAS 1202774-93-3)
- 1-(2-Chloro-4-fluorophenyl)butan-2-one (CAS 1248619-92-2)
- 1-(3-Chloro-4-fluorophenyl)-2-methylpropan-1-one (CAS 1266883-86-6)
Recommended Standards
- 1-(4-Chloro-3-fluorophenyl)butan-2-one (CAS 1443339-22-7)
- 3-(Chlorosulfonyl)-2,2-dimethylpropanoic acid (CAS 1506695-03-9)
- (2-Chloro-6-fluorophenyl)(cyclopropyl)methanol (CAS 1443312-38-6)
- 4-(4-Chloro-2-fluorophenyl)butan-2-one (CAS 1540370-13-5)
- N-(4-chlorophenyl)-1-(3,4-dimethylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide (CAS 866847-92-9)
- 4-Bromo-3-iodo-1H-pyrazole (CAS 27258-14-6)
- DHPTA (CAS 3148-72-9)
- 2-Chloro-9H-xanthen-9-one (CAS 13210-15-6)
- Penfluridol Impurity 1 (CAS 21928-50-7)
- (2R,3S,4S)-2-(Hydroxymethyl)-5-methoxytetrahydrofuran-3,4-diol (CAS 79083-42-4)
- (5-((5-Fluoro-2-methylphenyl)sulfonyl)-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 3,4-dichlorobenzoate (CAS 956262-86-5)
- diexo-(3-Amino-bicyclo[2.2.1]hept-5-en-2-yl)-methanol (CAS 95630-78-7)
- 1-((4-Methoxyphenyl)sulfonyl)pyrrolidin-3-amine (CAS 1242905-93-6)
- Semaglutide impurity 26 (CAS CATO-C4X-222626)
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