4-(4-Chloro-2-fluorophenyl)butan-2-one CAS 1540370-13-5
| CAS No. | 1540370-13-5 |
| Molecular Formula | C10H10ClFO |
| Molecular Weight | 200.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 200.64 g/mol gives 4-(4-Chloro-2-fluorophenyl)butan-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(4-Chloro-2-fluorophenyl)butan-2-one (CAS 1540370-13-5), molecular formula C10H10ClFO and molecular weight 200.64 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(4-Chloro-2-fluorophenyl)butan-2-one (C10H10ClFO) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(4-Chloro-2-fluorophenyl)butan-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10ClFO |
| Molecular Weight | 200.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-(2-Chloro-6-fluorophenyl)butan-2-one (CAS 1019769-64-2)
- 5-Chloro-3-fluoro-2-(pyrrolidin-1-yl)pyridine (CAS 1020253-18-2)
- 5-Chloro-2-thiobenzenesulfonyl fluoride (CAS 108158-05-0)
- 4-(2-Chloro-4-fluorophenyl)butan-2-one (CAS 1099621-26-7)
- 1-(2-Chloro-6-fluorophenyl)butan-2-one (CAS 1178854-65-3)
- (4-Chloro-2-fluorophenyl)(cyclopropyl)methanol (CAS 1202774-93-3)
- 1-(2-Chloro-4-fluorophenyl)butan-2-one (CAS 1248619-92-2)
- 1-(3-Chloro-4-fluorophenyl)-2-methylpropan-1-one (CAS 1266883-86-6)
Recommended Standards
- 3-(Chlorosulfonyl)-2,2-dimethylpropanoic acid (CAS 1506695-03-9)
- 4-(but-3-en-1-yloxy)-1-chloro-2-fluorobenzene (CAS 1555645-24-3)
- (4-Chloro-3-fluorophenyl)(cyclopropyl)methanol (CAS 1443342-24-2)
- 1-Chloro-4-ethoxy-3-fluoro-2-vinylbenzene (CAS 167683-92-3)
- 2,2-Dimethylchromane-6-carbonitrile (CAS 132685-98-4)
- 5-[4-(diethylamino)phenyl]-4-methyl-4h-1,2,4-triazole-3-thiol (CAS 669748-04-3)
- 2-Boc-5-bromo-1,2,3,4-tetrahydroisoquinolin-8-amine (CAS 1260763-55-0)
- 4,6-Dimethylimidazo[1,2-a:5,4-b']dipyridin-3-amine (CAS 96287-03-5)
- 4-Amino-3-(furan-2-yl)-1-(piperidin-1-yl)butan-1-one (CAS 1263208-08-7)
- 1-phenyl-3-(pyrrolidin-1-yl)propan-1-amine (CAS 113640-37-2)
- 3-Bromo-4-(5-tetrazolyl)benzoic Acid (CAS 1131615-11-6)
- N-(4-Cyclopropoxy-2-isopropoxyphenyl)methanesulfonamide (CAS 1243396-84-0)
- 4-((1-Methoxy-1-oxobutan-2-yl)amino)butanoic acid (Levetiracetam Impurity) (CAS 1543300-90-8)
- Semaglutide Impurity 5 (CAS 23406-82-8)
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