Ambroxol Impurity 9 CAS 1445719-53-8
| CAS No. | 1445719-53-8 |
| Molecular Formula | C13H16Br2N2O |
| Molecular Weight | 376.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ambroxol Impurity 9 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Ambroxol Impurity 9 (CAS 1445719-53-8), a pharmacopoeial impurity reference standard (molecular formula C13H16Br2N2O, MW 376.09 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ambroxol Impurity 9 (C13H16Br2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H16Br2N2O |
| Molecular Weight | 376.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Ambroxol Standards
- Ambroxol Impurity 103 (CAS 2499966-00-4)
- Ambroxol Impurity 11 (CAS CATO-C4X-108511)
- Ambroxol EP Impurity C (CAS 50910-53-7)
- Ambroxol EP Impurity D (CAS 107814-37-9)
- Ambroxol Impurity 35 (CAS 36557-04-7)
- Ambroxol (CAS 18683-91-5)
- Ambroxol EP Impurity D (CAS CATO-C4X-108545)
- Ambroxol Impurity 25 (CAS 1807328-39-7)
Recommended Standards
- 2,2,3,3,4,4,4-Heptafluorobutyl (2,2,3,3,3-pentafluoropropyl) carbonate (CAS 1980085-55-9)
- 2-(3,3,4,4,5,5,5-Heptafluoro-2,2-bis(trifluoromethyl)pentyl)oxirane (CAS 119285-89-1)
- 3-Perfluorohexyl-1,2-epoxypropane (CAS 38565-52-5)
- 2’,7’-Dibromospiro[cyclopent[3]ene-1,9’-fluorene] (CAS 951884-04-1)
- Alogliptin impurity 86 (CAS 2716884-59-0)
- Atogepant Impurity 31 (CAS 1375471-11-6)
- N-Nitroso Nafamostat impurity 116 (CAS CATO-C4X-1332116)
- 2-Bromo-3-iodo-6-(trifluoromethyl)pyridine (CAS 749875-08-9)
- 3-(Methyl carboxy)-4-(pyridin-3-yl)but-3-enoic acid (CAS 1415565-98-8)
- 1-(4-(2-Methoxyethoxy)phenyl)ethan-1-one (CAS 60893-75-6)
- (4-Amino-2-chlorophenyl)dimethylamine dihydrochloride (CAS 127951-77-3)
- 2-methylimidazo[1,2-a]pyrimidine-3-carboxylic acid (CAS 90830-11-8)
- 1-(Piperidin-1-yl)-2-(piperidin-4-yl)ethan-1-one hydrochloride (CAS 889100-47-4)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com