Cabazitaxel Impurity 51 CAS 1446010-46-3

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.1446010-46-3
Molecular FormulaC52H61NO15
Molecular Weight940.04 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Cabazitaxel Impurity 51 CAS 1446010-46-3 chemical structure

Description

CATO supplies Cabazitaxel Impurity 51 (CAS 1446010-46-3), a pharmacopoeial impurity reference standard (molecular formula C52H61NO15, MW 940.04 g/mol) used for the identification and quantification of trace impurities in APIs.

Cabazitaxel Impurity 51 (C52H61NO15) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC52H61NO15
Molecular Weight940.04 g/mol
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)23.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Nitrogen Atoms1

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