5-(((1R,1AS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one CAS 1446090-79-4
| CAS No. | 1446090-79-4 |
| Molecular Formula | C25H17F3N4O3 |
| Molecular Weight | 478.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 5-(((1R,1AS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one (CAS 1446090-79-4), a certified reference material (molecular formula C25H17F3N4O3, MW 478.42 g/mol) for analytical method development and quality control.
Structurally, 5-(((1R,1AS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one (C25H17F3N4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 18.0, corresponding to approximately 18 ring(s) or double-bond equivalent(s). With a molecular weight of 478.42 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H17F3N4O3 |
| Molecular Weight | 478.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Recommended Standards
- Benzofuran Impurity 3 (CAS 1446090-77-2)
- Apalutamide Impurity 72 (CAS 1950587-19-5)
- 4-Chloro-N-(2-(4-((4-chlorophenyl)sulfonyl)piperazin-1-yl)ethyl)benzenesulfonamide (CAS 547733-50-6)
- N-(2-Bromophenyl)-2-((3-ethyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 577960-68-0)
- 2-(2-Fluoro-6-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1246632-96-1)
- 2,2-Difluorobenzo[d][1,3]dioxol-5-ol (CAS 1211539-82-0)
- Ertapenem (CAS 153832-46-3)
- (S)-tert-Butyl 3-([1,1'-biphenyl]-4-yl)-2-aminopropanoate (CAS 225528-25-6)
- cis-2-ethoxy-4-[1-(3-iodo-1-bicyclo[1.1.1]pentanyl)-1-methyl-ethyl]tetrahydrofuran (CAS 2374231-14-6)
- 4-((5-Aminopyridin-2-yl)oxy)benzoic acid (CAS 887350-55-2)
- 1-(6-(2H-1,2,3-Triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl)-3-(7-(cyclopropyl(dimethylamino)methyl)-2-methylthiazolo[5,4-b]pyridin-6-yl)urea (CAS 2178991-05-2)
- Formoterol Impurity 95 (CAS CATO-C4X-152595)
- 2-(2-Fluoro-4-nitrophenyl)acetaldehyde (CAS 1160623-39-1)
- Insulin Degludec Impurity 3 (CAS CATO-C4X-21573)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com