Benzofuran Impurity 3 CAS 1446090-77-2
| CAS No. | 1446090-77-2 |
| Molecular Formula | C25H17F3N4O3 |
| Molecular Weight | 478.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Benzofuran Impurity 3 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Benzofuran Impurity 3 (CAS 1446090-77-2), a certified reference material (molecular formula C25H17F3N4O3, MW 478.42 g/mol) for analytical method development and quality control.
Benzofuran Impurity 3 (C25H17F3N4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H17F3N4O3 |
| Molecular Weight | 478.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Benzofuran Standards
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- (S)-(3-((2-(4-(Benzofuran-5-yl)phenyl)-1H-imidazo[4,5-c]pyridin-1-yl)methyl)pyrrolidin-1-yl)(cyclopropyl)methanone (CAS 1309805-49-9)
- 3-(Benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)propan-1-one (CAS 209746-56-5)
- N-(4-(Benzofuran-2-yl)-6-methylbenzo[d]thiazol-2-yl)-2-(2,3-dihydrobenzofuran-5-yl)acetamide (CAS 2288708-59-6)
- 4-(Benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one (CAS 618369-75-8)
- 4-(Benzofuran-2-carbonyl)-5-(4-chlorophenyl)-3-hydroxy-1-(5-methylisoxazol-3-yl)-1,5-dihydro-2H-pyrrol-2-one (CAS 618877-26-2)
- (S)-4-(4-(Benzofuran-5-yl)phenyl)-3-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)methyl)-1H-1,2,4-triazol-5(4H)-one (CAS 1332331-08-4)
Recommended Standards
- 4-Chloro-N-(2-(4-((4-chlorophenyl)sulfonyl)piperazin-1-yl)ethyl)benzenesulfonamide (CAS 547733-50-6)
- 5-(((1R,1AS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one (CAS 1446090-79-4)
- 4,4'-([1,1'-Biphenyl]-4,4'-diylbis(oxy))bis(isobenzofuran-1,3-dione) (CAS 53303-54-1)
- Apalutamide Impurity 72 (CAS 1950587-19-5)
- 4-Bromopyrazolo[1,5-a]pyridine (CAS 1427404-87-2)
- 2-Chloro-N-(4-chloro-2-fluorophenyl)benzamide (CAS 546067-70-3)
- 1-Isopropyl-1H-pyrazole-4,5-diamine (CAS 155601-16-4)
- 6'-Methoxy-5-methyl-2,2'-bipyridine (CAS 638353-16-9)
- 7-bromo-2,4-dichloro-6,8-difluoro-quinazoline (CAS 2248318-27-4)
- 5-Allyl-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid (CAS 1822545-77-6)
- 2,3-Diethyl-2-cyclopropen-1-one (CAS 65864-10-0)
- 1-(2,4-Difluorophenyl)-2-(methylthio)propan-1-one (CAS 133825-95-3)
- 3-Ethoxypropanethioamide (CAS 1016780-86-1)
- Tirzepatide Impurity 48 (CAS CATO-C4X-324048)
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