Linagliptin Impurity 7 CAS 1446263-38-2
| CAS No. | 1446263-38-2 |
| Molecular Formula | C25H28N8O2 |
| Molecular Weight | 472.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 472.54 g/mol gives Linagliptin Impurity 7 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Linagliptin Impurity 7 (CAS 1446263-38-2, C25H28N8O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Linagliptin Impurity 7 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 472.54 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Linagliptin Impurity 7 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H28N8O2 |
| Molecular Weight | 472.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 8 |
Related Linagliptin Standards
- Linagliptin (CAS 668270-12-0)
- Linagliptin Impurity 122 (CAS 2446799-72-8)
- Linagliptin impurity 137 (CAS CATO-C4X-1101137)
- Linagliptin impurity 141 (CAS CATO-C4X-1101141)
- Linagliptin impurity 154 (CAS 1383917-84-7)
- Linagliptin Form A (CAS CATO-C4X-1101157)
- Linagliptin Impurity 52 (CAS 2463617-43-6)
- Linagliptin Impurity 9 (CAS 668270-11-9)
Recommended Standards
- Liglitide Form B (CAS CATO-C4X-1101158)
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- (S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-3-oxoisoindolin-4-yl)cyclopropanecarboxamide (CAS 340019-69-4)
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- Afatinib Impurity 59 (CAS 618061-77-1)
- 5-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indole (CAS 1188178-71-3)
- 73571-20-7 Pyridine, 3-methyl-5-phenoxy- (CAS 73571-20-7)
- [2-(hydroxymethyl)naphthalen-1-yl]methanol (CAS 39050-28-7)
- Dendroaspis Natriuretic Peptide (CAS 255721-52-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com