Istradefylline impurity 31 CAS CATO-C4X-106131
| CAS No. | CATO-C4X-106131 |
| Molecular Formula | C20H24N4O4 |
| Molecular Weight | 384.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Istradefylline impurity 31 (C20H24N4O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Istradefylline impurity 31 (CAS CATO-C4X-106131, C20H24N4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Istradefylline impurity 31 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H24N4O4 |
| Molecular Weight | 384.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Istradefylline Standards
- Istradefylline (CAS 155270-99-8)
- Istradefylline Impurity 1 (CAS 606080-73-3)
- Istradefylline Impurity 22 (CAS 1453190-01-6)
- Istradefylline Impurity 6 (CAS CATO-C4X-10616)
- Istradefylline Impurity 23 (CAS 187393-68-6)
- Istradefylline impurity 30 (CAS CATO-C4X-106130)
- Istradefylline Impurity 9 (CAS CATO-C4X-10619)
- Istradefylline Impurity 2 (CAS 160434-48-0)
Recommended Standards
- Dabigatran Impurity 133 (CAS CATO-C4X-1089133)
- Rilpivirine Impurity 12 (CAS 1446439-51-5)
- 4-(4-(4-(4-aMinophenoxy)phenoxy)phenoxy)benzenaMine (CAS 13080-88-1)
- Rilpivirine Amide (CAS 500288-66-4)
- Nafamostat Impurity 13 (CAS CATO-C4X-133213)
- Bumetanide Impurity 132 (CAS CATO-C4X-1986132)
- Empagliflozin Impurity 66 (CAS 2744280-76-8)
- Lasiocarpine N-Oxide (CAS 127-30-0)
- N-(4-amino-2-methylphenyl)isonicotinamide (CAS 33974-32-2)
- 2-Cyclopropoxy-1,3-diiodobenzene (CAS 1243449-09-3)
- n-Ethyl-N-(pyrrolidin-3-yl)butyramide (CAS 1184493-16-0)
- n-(4,5,6,7-Tetrahydrothiazolo[5,4-c]pyridin-2-yl)thiophene-2-carboxamide (CAS 1082576-98-4)
- 3,3'-((3,6-Dioxocyclohexa-1,4-diene-1,4-diyl)bis(azanediyl))bis(N-benzyl-N,N-diethylpropan-1-aminium) chloride (CAS 311-09-1)
- Peptide-GMF (CAS CATO-CPTD788469)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com