Afatinib Impurity 53 CAS 1449430-45-8
Purity >95%In StockPharmacopoeial Impurity Standards
| CAS No. | 1449430-45-8 |
| Molecular Formula | C14H8ClFN4O3 |
| Molecular Weight | 334.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Afatinib Impurity 53 (CAS 1449430-45-8) is a high-purity pharmacopoeial impurity standards reference standard from CATO, an ISO 17034 accredited reference material producer. Molecular formula: C14H8ClFN4O3. Molecular weight: 334.69 g/mol. Each batch is supplied with a Certificate of Analysis (COA).
Physical & Chemical Properties
| Molecular Formula | C14H8ClFN4O3 |
| Molecular Weight | 334.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Afatinib Standards
- Afatinib Impurity 83 (CAS CATO-C4X-100683)
- Afatinib Impurity 22 (CAS 162012-67-1)
- Afatinib Impurity 51 (CAS CATO-C4X-100651)
- Afatinib Impurity 54 (CAS 2831861-00-6)
- Afatinib Impurity 80 (CAS CATO-C4X-100680)
- Afatinib Impurity 81 (CAS CATO-C4X-100681)
- Afatinib Impurity 65 (CAS CATO-C4X-100665)
- Afatinib Impurity 76 (CAS CATO-C4X-100676)
Recommended Standards
- Ethyl 3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-5-methyl-1,2-oxazole-4-carboxylate (CAS 303997-38-8)
- 1-(3-Chloro-4-fluorophenyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-76-4)
- Carpropamid (CAS 104030-54-8)
- Penfluridol Impurity 8 (CAS 77294-14-5)
- Zopiclone Impurity 16 (CAS 59325-11-0)
- (2S,4R)-1-((S)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 2097971-11-2 (CAS 2097971-11-2)
- (3,3-dimethylcyclobutyl)hydrazine;dihydrochloride (CAS 2231674-83-0)
- N-(4-(1-Aminoethyl)phenyl)cyclopropanecarboxamide (CAS 953734-60-6)
- 1,4-Diamino-6-chloro-2-phenoxyanthracene-9,10-dione (CAS 88623-57-8)
- Semaglutide impurity 104(Fmoc-D-His-Aib) (CAS 2171211-18-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 13829788188 / jacky.chen@cato-chem.com