Prilocaine Hydrochloride EP Impurity G CAS 145133-92-2
| CAS No. | 145133-92-2 |
| Molecular Formula | C12H18N2O |
| Molecular Weight | 206.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Prilocaine Hydrochloride EP Impurity G (CAS 145133-92-2) is a certified pharmaceutical impurity reference standard with the molecular formula C12H18N2O and a molecular weight of 206.28 g/mol.
The molecular framework of Prilocaine Hydrochloride EP Impurity G (C12H18N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Prilocaine Hydrochloride EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H18N2O |
| Molecular Weight | 206.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 2 |
Related Prilocaine Standards
- Prilocaine EP Impurity C (CAS 42459-37-0)
- Prilocaine EP Impurity F (CAS 42459-45-0)
- Prilocaine Impurity 59 (CAS 99865-77-7)
- Prilocaine Impurity C56 (CAS 111057-88-6)
- Prilocaine Impurity N3 (CAS 147372-41-6)
- Prilocaine EP Impurity A (CAS 19281-31-3)
- Prilocaine Impurity 10 (CAS CATO-C4X-193410)
- Prilocaine Impurity 12 (CAS 19422-76-5)
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