Prilocaine Impurity 12 CAS 19422-76-5
| CAS No. | 19422-76-5 |
| Molecular Formula | C10H12ClNO |
| Molecular Weight | 197.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Prilocaine Impurity 12.
As a process- or degradation-related impurity, Prilocaine Impurity 12 (CAS 19422-76-5, C10H12ClNO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Prilocaine Impurity 12 (C10H12ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Prilocaine Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12ClNO |
| Molecular Weight | 197.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Prilocaine Standards
- Prilocaine Impurity C56 (CAS 111057-88-6)
- Prilocaine Impurity N3 (CAS 147372-41-6)
- Prilocaine EP Impurity A (CAS 19281-31-3)
- Prilocaine Impurity 10 (CAS CATO-C4X-193410)
- Prilocaine Impurity 7 (CAS 39106-10-0)
- Prilocaine Impurity 22 (CAS 2384559-40-2)
- Prilocaine EP Impurity C (CAS 42459-37-0)
- Prilocaine Hydrochloride EP Impurity G (CAS 145133-92-2)
Recommended Standards
- Tolvaptan Impurity 33 (CAS 1310357-40-4)
- Etomidate impurity 64 (CAS 36293-00-2)
- N-((6-Chloropyridin-3-yl)methyl)-N-methylacetimidamide (CAS 365441-66-3)
- Lidocaine EP Impurity H (CAS 1131-01-7)
- Amisulpride Impurity 19 (CAS 483304-03-6)
- Talazoparib Impurity 2 (CAS CATO-C4X-33732)
- Levodopa Impurity 17 (CAS 27313-65-1)
- (R)-tert-Butyl 3-(2-chloro-N-isopropylacetamido)pyrrolidine-1-carboxylate (CAS 1353994-81-6)
- 2-(5-Amino-3-isopropyl-4-(methylsulfonyl)-1H-pyrazol-1-yl)ethanol (CAS 1713476-54-0)
- (R)-6,7-Dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 792898-30-7)
- 1-Benzhydryl-3-hydrazinylazetidine (CAS 1025899-41-5)
- N3,N3,N3''',N3'''-TEtra-p-tolyl-[1,1':2',1'':2'',1'''-quaterphenyl]-3,3'''-diamine (CAS 869357-89-1)
- 2-Methyl-5-phenylpyrimidin-4(1H)-one (CAS 343944-83-2)
- Semaglutide Sodium Salt (CAS CATO-C4X-222620)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com