Triclabendazole Impurity 4 CAS 145770-89-4

Description

Compared with other compounds in its class, the molecular weight of 373.68 g/mol gives Triclabendazole Impurity 4 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Triclabendazole Impurity 4 (CAS 145770-89-4) is a certified pharmaceutical impurity reference standard with the molecular formula C15H11Cl3N2OS and a molecular weight of 373.68 g/mol.

Based on its molecular formula C15H11Cl3N2OS, Triclabendazole Impurity 4 contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 373.68 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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