Cilnidipine Impurity 7 CAS 146845-35-4
| CAS No. | 146845-35-4 |
| Molecular Formula | C27H26N2O7 |
| Molecular Weight | 490.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cilnidipine Impurity 7.
As a process- or degradation-related impurity, Cilnidipine Impurity 7 (CAS 146845-35-4, C27H26N2O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cilnidipine Impurity 7 (C27H26N2O7) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Cilnidipine Impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H26N2O7 |
| Molecular Weight | 490.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 2 |
Related Cilnidipine Standards
- Cilnidipine Impurity 6 (CAS 146845-34-3)
- Cilnidipine Impurity 30 (CAS CATO-C4X-179630)
- Z-Cilnidipine Impurity 5 (CAS 146924-45-0)
- Cilnidipine (CAS 132203-70-4)
- Cilnidipine Impurity 1 (CAS CATO-C4X-17961)
- Cilnidipine-D7 (CAS 132203-70-4 (non-labelled))
- Cilnidipine Impurity 13 (CAS 1974323-06-2)
- Cilnidipine impurity 25 (CAS 2197014-75-6)
Recommended Standards
- Maribavir Impurity 11 (CAS CATO-C4X-300711)
- Trelagliptin Impurity 59 (CAS CATO-C4X-104659)
- Maribavir Impurity 13 (CAS CATO-C4X-300713)
- Trelagliptin Impurity 2 (CAS CATO-C4X-10462)
- Mirogabalin Impurity 171 (CAS CATO-C4X-2924171)
- N-Nitroso Cetirizine EP Impurity A (CAS 2005-04-1)
- Erlotinib Impurity 144 (CAS CATO-C4X-1069144)
- Ethyl 4-chloro-5-hydroxynicotinate (CAS 1805460-11-0)
- 4-cyano-1H-indazole-3-carboxylic acid (CAS 1000341-33-2)
- 2,4-difluoro-3-iodo-pyridine (CAS 837364-88-2)
- 2-bromo-5-methoxybenzenecarbothioamide (CAS 1114822-69-3)
- 2-chloro-6-ethoxypyrazine (CAS 136309-02-9)
- N1-(4-Methoxy-2-nitrophenyl)-1,2-ethanediamine (CAS 13556-31-5)
- Serpent Peptide 2AcOH (CAS 823202-99-9(free base))
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