Lumateperone Impurity 18 CAS 1469343-42-7
| CAS No. | 1469343-42-7 |
| Molecular Formula | C24H30FN3O |
| Molecular Weight | 395.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Lumateperone Impurity 18 (CAS 1469343-42-7, C24H30FN3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Lumateperone Impurity 18 (C24H30FN3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 395.51 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H30FN3O |
| Molecular Weight | 395.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Lumateperone Standards
- Lumateperone Impurity 50 (CAS 2117618-98-9)
- Lumateperone impurity 60 (CAS CATO-C4X-220160)
- Lumateperone Impurity 71 (CAS CATO-C4X-220171)
- Lumateperone Impurity 76 (CAS CATO-C4X-220176)
- Lumateperone (CAS 313368-91-1)
- Lumateperone Impurity 1 (CAS 313368-92-2)
- Lumateperone Impurity 2 (CAS 1576240-15-7)
- Lumateperone Impurity 3 (CAS CATO-C4X-22013)
Recommended Standards
- Blonanserin Impurity 24 (CAS CATO-C4X-111024)
- Cariprazine Impurity 27 (CAS CATO-C4X-240827)
- N-(4-Cyclohexylphenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide (CAS 882082-17-9)
- Cariprazine Impurity 65 (CAS CATO-C4X-240865)
- Dalilesen impurity 38 (CAS 1505484-57-0)
- Ambroxol Impurity 85 (CAS CATO-C4X-108585)
- Bacitracin Impurity L (CAS CATO-C4X-155312)
- epimeridinoside (CAS 848599-79-1)
- 5-[(3-Chlorophenyl)sulfanyl]-N-(2,4-difluorophenyl)-1,3-dimethyl-1H-pyrazole-4-carboxamide (CAS 158712-51-7)
- 2-(2-Aminopyrimidin-4-yl)-4-methylphenol (CAS 925003-40-3)
- N-(2-(1-Acetyl-5-(quinolin-8-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide (CAS 923139-61-1)
- 2-Bromonaphthalene-1,2,3,4,4a,8a-13C6 (CAS 1262053-54-2)
- (5-Chloro-2-methoxypyridin-3-yl)boronic acid (CAS 943153-22-8)
- Neuropeptide K, porcine (CAS 106441-70-7)
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