Lumateperone Impurity 76 CAS CATO-C4X-220176
| CAS No. | CATO-C4X-220176 |
| Molecular Formula | C17H21BrN2O4 |
| Molecular Weight | 397.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Lumateperone Impurity 76 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Lumateperone Impurity 76 (CAS CATO-C4X-220176) is a certified pharmaceutical impurity reference standard with the molecular formula C17H21BrN2O4 and a molecular weight of 397.26 g/mol.
The molecular framework of Lumateperone Impurity 76 (C17H21BrN2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lumateperone Impurity 76 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H21BrN2O4 |
| Molecular Weight | 397.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Lumateperone Standards
- Lumateperone-D4 (CAS 2135466-52-1)
- Lumateperone impurity 60 (CAS CATO-C4X-220160)
- Lumateperone Impurity 71 (CAS CATO-C4X-220171)
- Lumateperone Impurity 18 (CAS 1469343-42-7)
- Lumateperone Impurity 50 (CAS 2117618-98-9)
- Lumateperone (CAS 313368-91-1)
- Lumateperone Impurity 1 (CAS 313368-92-2)
- Lumateperone Impurity 2 (CAS 1576240-15-7)
Recommended Standards
- Tert-butyl 6-bromo-4-oxo-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidine]-1'-carboxylate (CAS 690632-05-4)
- tert-Butyl 4-(3-bromo-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate (CAS 1923811-12-4)
- N-(5-((2,6-Dichlorobenzyl)oxy)pyrazin-2-yl)-2-morpholinoacetamide (CAS 642084-65-9)
- (E)-1-(2-chloro-6-fluorobenzyl)-2-(2-chlorostyryl)-1H-benzo[d]imidazole (CAS 338772-13-7)
- Bupropion Impurity 50 (CAS 1483-01-8)
- Rizatriptan Impurity 26 (CAS 1391062-44-4)
- Zuranolone impurity 2 (CAS CATO-C4X-30382)
- Ethyl 2-(1-hydroxycyclooctyl)acetate (CAS 5095-70-5)
- 5-(4-Aminophenyl)-2,3-dihydro-1h-pyrazol-3-one (CAS 908254-18-2)
- Pretilachlor (CAS 51218-49-6)
- 2-Amino-7-bromo-4-(4-chloro-3-nitrophenyl)-4H-benzo[g]chromene-3-carbonitrile (CAS 861208-32-4)
- 2-(3-Amino-4-bromo-1H-pyrazol-1-yl)acetic acid (CAS 1006320-13-3)
- Methyl 4-methyl-3-propionamidothiophene-2-carboxylate (CAS 1779088-71-9)
- Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 330456-24-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com