Emtricitabine impurity 53 CAS 147027-01-8
| CAS No. | 147027-01-8 |
| Molecular Formula | C18H26FN3O4S |
| Molecular Weight | 399.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Emtricitabine impurity 53 (CAS 147027-01-8, C18H26FN3O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Emtricitabine impurity 53 (C18H26FN3O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Emtricitabine impurity 53 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H26FN3O4S |
| Molecular Weight | 399.48 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Emtricitabine Standards
- Emtricitabine Impurity 16 (CAS 764659-79-2)
- Emtricitabine Menthyl Ester Impurity (CAS 764659-72-5)
- Emtricitabine Impurity 30 (CAS 147126-75-8)
- Emtricitabine Impurity 57 (CAS 1773498-61-5)
- Emtricitabine Impurity 59 (CAS 1422361-25-8)
- Emtricitabine O-β-D-Glucuronide (CAS 152128-78-4)
- Emtricitabine Impurity 36 (CAS CATO-C4X-123236)
- Emtricitabine Isopropyl Carbamate (CAS CATO-C4X-123217)
Recommended Standards
- Salbutamol Impurity 125 (CAS CATO-C4X-1176125)
- Nitroso Perindopril EP impurity N (CAS CATO-C4X-125251)
- Rosuvastatin Impurity 225 (CAS CATO-C4X-1169225)
- Deflazacort Impurity 1 (CAS 13649-57-5)
- Linezolid Impurity 67 (CAS CATO-C4X-107367)
- Upadacitinib Impurity 78 (CAS 2411540-30-0)
- Diltiazem EP Impurity E (CAS 42399-49-5)
- Tauromustine (CAS 85977-49-7)
- 2-(Dimethoxymethyl)dihydro-3(2H)-furanone (CAS 287183-59-9)
- 2-((1-Methylpyrrolidin-3-yl)methoxy)ethan-1-amine (CAS 1353957-27-3)
- Ertugliflozin Impurity 47 (CAS 2755949-10-9)
- 5-(Methylamino)piperidin-2-one (CAS 1343353-65-0)
- 3-(2,3,4-trifluorophenyl)cyclohex-2-en-1-one (CAS 1513178-99-8)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com