(2R,5R)-Lamivudine Impurity 37 CAS 147126-80-5
| CAS No. | 147126-80-5 |
| Molecular Formula | C18H27N3O4S |
| Molecular Weight | 381.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies (2R,5R)-Lamivudine Impurity 37 (CAS 147126-80-5), a pharmacopoeial impurity reference standard (molecular formula C18H27N3O4S, MW 381.49 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, (2R,5R)-Lamivudine Impurity 37 (C18H27N3O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 381.49 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H27N3O4S |
| Molecular Weight | 381.49 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Recommended Standards
- (1S,2R,5S)-Lamivudine Impurity 36 (CAS 147126-72-5)
- Lamivudine Impurity 45 (CAS CATO-C4X-119445)
- ent-Lamivudine (1S,2R,5S)-5-Methyl-2-isopropylcyclohexyl Ester (CAS 147126-74-7)
- Lumateperone Impurity 51 (CAS 1469777-40-9)
- Ceftizoxime Impurity 15 (CAS 54639-48-4)
- Lomefloxacin Impurity 24 HCl (CAS CATO-C4X-207324)
- Glumetinib Impurity 6 (CAS CATO-C4X-32596)
- 2-Amino-n-(4-iodophenyl)ethane-1-sulfonamide (CAS 1039323-63-1)
- N-(5-amino-2-methylphenyl)-3-chlorobenzamide (CAS 926251-00-5)
- spiro[indene-2,3'-piperidin]-1(3H)-one (CAS 203797-64-2)
- 5-(2-Methyl-1,3-dioxolan-2-yl)-2-pyridineethanol (CAS 184766-50-5)
- 3,5-Dichloro-4-methylbenzotrifluoride (CAS 1803837-95-7)
- Nintedanib Demethyl-O-Glucuronide (CAS 1352789-50-4)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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