Dorzolamide Impurity 5 CAS CATO-C4X-12285
| CAS No. | CATO-C4X-12285 |
| Molecular Formula | C10H14N2O5S3 |
| Molecular Weight | 338.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Dorzolamide Impurity 5 (CAS CATO-C4X-12285, C10H14N2O5S3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C10H14N2O5S3, Dorzolamide Impurity 5 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 338.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14N2O5S3 |
| Molecular Weight | 338.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 3 |
Related Dorzolamide Standards
- Dorzolamide Impurity 22 (CAS 147128-79-8)
- Dorzolamide N-Desethyl N-Acetyl Impurity (CAS 147200-03-1)
- Dorzolamide-d5 (CAS 1227097-70-2)
- Dorzolamide Impurity 13 (CAS 897657-78-2)
- Dorzolamide (CAS 120279-96-1)
- Rac-Dorzolamide (CAS 120280-13-9)
- Dorzolamide (CAS 139066-77-6)
- Dorzolamide EP Impurity B（R,S-Isomer) (CAS 149249-72-9)
Recommended Standards
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- Daptomycin impurity 45 (CAS CATO-C4X-137845)
- Cefminox Impurity 40 (CAS CATO-C4X-192640)
- Upadacitinib Impurity 144 (CAS CATO-C4X-2405144)
- 2-Chloroethyl methanesulfonate (CAS 3570-58-9)
- 1-(2-Fluorophenyl)-4-{[2-(4-methoxyphenyl)imidazo[1,2-a]pyridin-3-yl]methyl}piperazine (CAS 338415-61-5)
- 2-(Methylsulfonyl)-N-((5-methylthiophen-2-yl)methyl)ethan-1-amine (CAS 1178475-88-1)
- 2-Chloro-N'-(2-(4-methoxyphenyl)imidazo[1,2-a]pyridine-6-carbonyl)benzenesulfonohydrazide (CAS 866137-85-1)
- Dicyclohexano-18-crown-6 (CAS 29515-99-9)
- 2-Methyl-6-nitroquinoline (CAS 613-30-9)
- (Tyr?)-C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 142878-79-3)
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