Pomalidomide Impurity 61 CAS 147291-59-6
| CAS No. | 147291-59-6 |
| Molecular Formula | C13H16N2O6 |
| Molecular Weight | 296.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Pomalidomide Impurity 61 (CAS 147291-59-6) is a certified pharmaceutical impurity reference standard with the molecular formula C13H16N2O6 and a molecular weight of 296.28 g/mol.
The molecular framework of Pomalidomide Impurity 61 (C13H16N2O6) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Pomalidomide Impurity 61 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H16N2O6 |
| Molecular Weight | 296.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 2 |
Related Pomalidomide Standards
- Pomalidomide Impurity 54 (CAS CATO-C4X-135454)
- Pomalidomide Impurity 58 (CAS 18658-36-1)
- Pomalidomide Impurity 55 (CAS CATO-C4X-135455)
- Pomalidomide Impurity 1 (CAS 1001852-14-7)
- Pomalidomide Impurity 2 (CAS 1001852-15-8)
- Pomalidomide Impurity 3 (CAS 2635-64-5)
- Pomalidomide Impurity 4 (CAS 918314-45-1)
- Pomalidomide Impurity 11 (CAS 19171-18-7)
Recommended Standards
- Levosimendan Impurity 27 (CAS CATO-C4X-130827)
- Dolutegravir Impurity 51 (CAS CATO-C4X-162051)
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- Iguratimod Impurity 19 (CAS CATO-C4X-182619)
- Dabigatran Impurity 137 (CAS CATO-C4X-1089137)
- Cefdinir Impurity C84 (CAS 178422-45-2)
- Azilsartan Impurity 182 (CAS CATO-C4X-1096182)
- 3',5'-Dichloro-2,2,2-trifluoroacetophenone (CAS 130336-16-2)
- 6-Oxo-N-(2-(thiophen-2-yl)ethyl)-1,6-dihydropyridine-3-carboxamide (CAS 1031128-36-5)
- tert-butyl N-[2-(propan-2-yloxy)pyridin-4-yl]carbamate (CAS 1936610-26-2)
- 3-Cyclopropyltetrahydrofuran-3-ol (CAS 1416438-43-1)
- 2-(5-Phenylpyridin-2-yl)acetonitrile (CAS 1227606-86-1)
- 5-{[(1-methyl-1H-imidazol-2-yl)sulfanyl]methyl}furan-2-carboxylic acid (CAS 923675-20-1)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
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