1-(3-Chloro-4-fluorophenyl)-3-cyclopropylpropan-1-one CAS 1477686-15-9
| CAS No. | 1477686-15-9 |
| Molecular Formula | C12H12ClFO |
| Molecular Weight | 226.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(3-Chloro-4-fluorophenyl)-3-cyclopropylpropan-1-one (CAS 1477686-15-9), molecular formula C12H12ClFO and molecular weight 226.67 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 1-(3-Chloro-4-fluorophenyl)-3-cyclopropylpropan-1-one is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 226.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12ClFO |
| Molecular Weight | 226.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
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- Doxapram Impurity 44 (CAS CATO-C4X-197344)
- (2E)-3-(Dimethylamino)-2-[(E)-5-[3-(trifluoromethyl)phenoxy]pyridine-2-carbonyl]prop-2-enenitrile (CAS 866152-31-0)
- 1,2,3,5,7-Pentachloronaphthalene (CAS 53555-65-0)
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- Dodecanedioic acid diethyl ester (CAS 10471-28-0)
- His-Cyclic-Semaglutide (CAS CATO-C4X-2226182)
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