(5-Chloro-2-fluorophenyl)(cyclopentyl)methanone CAS 1368672-87-0
| CAS No. | 1368672-87-0 |
| Molecular Formula | C12H12ClFO |
| Molecular Weight | 226.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (5-Chloro-2-fluorophenyl)(cyclopentyl)methanone.
(5-Chloro-2-fluorophenyl)(cyclopentyl)methanone (CAS 1368672-87-0), molecular formula C12H12ClFO and molecular weight 226.67 g/mol, is a CATO reference standard with documented purity and traceability.
(5-Chloro-2-fluorophenyl)(cyclopentyl)methanone (C12H12ClFO) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12ClFO |
| Molecular Weight | 226.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 5-(2-(4-Chloro-3,5-dimethyl-1h-pyrazol-1-yl)ethyl)-2h-tetrazole (CAS 1005566-25-5)
- (2-Chloro-6-fluorophenyl)(cyclopentyl)methanone (CAS 1443342-98-0)
- (2-Chloro-5-fluorophenyl)(cyclopentyl)methanone (CAS 1443343-11-0)
- 1-(3-Chloro-4-fluorophenyl)-3-cyclopropylpropan-1-one (CAS 1477686-15-9)
- 1-((4-Chloro-1,3-dimethyl-1h-pyrazol-5-yl)methyl)-1h-1,2,3-triazol-4-amine (CAS 1525902-72-0)
- (2-Chloro-4-fluorophenyl)(cyclopentyl)methanone (CAS 898791-70-3)
- (3-Chloro-4-fluorophenyl)(cyclopentyl)methanone (CAS 898791-62-3)
- (3-Chloro-5-fluorophenyl)(cyclopentyl)methanone (CAS 898791-72-5)
Recommended Standards
- Chloridazon-d5 (Major) (CAS 1246818-99-4)
- Nerandomilast impurity 6 (CAS CATO-C4X-34736)
- Lornoxicam Impurity 1 (CAS 187746-97-0)
- Prilocaine impurity 61 (CAS CATO-C4X-193461)
- 1-((4-(Nonyloxy)phenyl)amino)anthracene-9,10-dione (CAS 75395-76-5)
- 3-(4-Chlorobenzylidene)-6-(trifluoromethyl)indolin-2-one (CAS 35315-58-3)
- Tert-butyl 3-carbamoyl-3-hydroxyazetidine-1-carboxylate (CAS 2092384-08-0)
- 1,3,3-Trimethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 41565-97-3)
- (1-(Pyridin-2-yl)pyrrolidin-2-yl)methanol (CAS 1247507-96-5)
- Benzyl 2-(Acetylamino)-3-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-2-deoxy-α-D-galactopyranoside (CAS 85054-29-1)
- Candesartan Impurity 6 (CAS CATO-C4X-15726)
- 3-Fluoro-6-(pyrrolidin-1-yl)pyridazine (CAS 2060063-58-1)
- 2-Ethyl-1,2-dihydro-3h-1,2,4-triazol-3-imine hydrochloride (CAS 1255717-34-0)
- Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 2022956-56-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com