Fluorouracil Impurity 10 CAS 1480-96-2
| CAS No. | 1480-96-2 |
| Molecular Formula | C5H5FN2O2 |
| Molecular Weight | 144.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Fluorouracil Impurity 10 (C5H5FN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 144.10 g/mol, it falls into the low-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Fluorouracil Impurity 10 (CAS 1480-96-2), a pharmacopoeial impurity reference standard (molecular formula C5H5FN2O2, MW 144.10 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5FN2O2 |
| Molecular Weight | 144.10 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorouracil Standards
- Fluorouracil Impurity 3 (CAS 4840-69-1)
- Fluorouracil EP Impurity D (CAS 6623-81-0)
- Fluorouracil Impurity 22 (CAS CATO-C4X-164922)
- Fluorouracil Impurity 30 (CAS CATO-C4X-164930)
- Fluorouracil Impurity 12 (CAS 155-16-8)
- Fluorouracil Impurity 26 (CAS 62836-98-0)
- Fluorouracil EP Impurity E (CAS 1820-81-1)
- Fluorouracil Impurity 11 (Mixture of Diastereomers) (CAS 37103-91-6)
Recommended Standards
- 5-Fluoro-6-methoxy-2(1H)-pyrimidinone (CAS 22462-35-7)
- (1H-Imidazol-2-yl)dimethylphosphine oxide (CAS 1009112-25-7)
- Methyl 5-fluoro-1H-pyrazole-3-carboxylate (CAS 2200261-27-2)
- 5-Fluoro-2-hydrazinylpyrimidin-4(3H)-one (CAS 1417349-42-8)
- Phloroglucinol Impurity 75 (CAS CATO-C4X-221775)
- Dexamethasone impurity 65 (CAS 1202002-01-4)
- Valproate Impurity 37 (CAS 62391-98-4)
- (2,2-Difluoroethyl)(propan-2-yl)amine hydrochloride (CAS 1394768-25-2)
- 5-Fluoroisoindoline-1,3-dione (CAS 94514-21-3)
- 3-Chloro-4-methyl-1-benzothiophene-2-carbohydrazide (CAS 956576-51-5)
- 6-Bromoimidazo[1,2-a]pyridine-3-carbonitrile (CAS 474708-98-0)
- 2-Chloro-3-(difluoromethyl)-4,5-diiodopyridine (CAS 1805329-84-3)
- 8-{[(9H-fluoren-9-yl)methoxy]carbonyl}-1-oxa-2,8-diazaspiro[4.5]dec-2-ene-3-carboxylic acid (CAS 1803562-58-4)
- D-γ-Glu20-Side-Tirzepatide (CAS CATO-CPTD788929)
Why CATO?
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