Dexamethasone impurity 65 CAS 1202002-01-4
| CAS No. | 1202002-01-4 |
| Molecular Formula | C22H30FO8P |
| Molecular Weight | 472.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dexamethasone impurity 65.
CATO supplies Dexamethasone impurity 65 (CAS 1202002-01-4), a pharmacopoeial impurity reference standard (molecular formula C22H30FO8P, MW 472.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Dexamethasone impurity 65 (C22H30FO8P) contains a flavonoid core, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dexamethasone impurity 65 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H30FO8P |
| Molecular Weight | 472.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone Impurity 108 (CAS CATO-C4X-1165108)
- Dexamethasone Impurity 109 (CAS CATO-C4X-1165109)
- Dexamethasone Impurity 117 (CAS CATO-C4X-1165117)
- Dexamethasone Impurity 128 (CAS CATO-C4X-1165128)
- Dexamethasone Sodium Phosphate EP Impurity C (CAS CATO-C4X-116522)
- Dexamethasone Sodium Phosphate Impurity B (CAS 360-63-4)
- Dexamethasone Sodium Phosphate EP Impurity D (CAS CATO-C4X-116528)
- Dexamethasone Sodium Phosphate EP Impurity E (CAS CATO-C4X-116529)
Recommended Standards
- Dexamethasone impurity 64 (CAS CATO-C4X-116564)
- Betamethasone impurity 103 (CAS CATO-C4X-1437103)
- Dexamethasone impurity 63 (CAS 1202001-99-7)
- Betamethasone Impurity 132 (CAS CATO-C4X-1437132)
- Tamsulosin Impurity 63 (CAS CATO-C4X-118763)
- Atrasentan Impurity 145 (CAS 1058350-11-0)
- Cabotegravir Impurity 19 (CAS CATO-C4X-287619)
- 1-Hydroxytetrahydropyrimidin-2(1H)-one (CAS 63656-07-5)
- N-allyl-3-phenylpropiolamide (CAS 95969-91-8)
- 3-Bromo-2-methylbenzofuran (CAS 58863-48-2)
- 5,6,7,8-Tetrahydropyrrolo[3,2-c]azepin-4(1H)-one (CAS 21357-23-3)
- 1-(2,2,2-trifluoroethoxy)propan-2-ol (CAS 133023-73-1)
- Methyl 3-(6-methoxy-1-(p-tolyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-2-carboxamido)thiophene-2-carboxylate (CAS 931941-76-3)
- Insulin Pork(≥27 USP units/mg) (CAS 12584-58-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com