Pimecrolimus Impurity 18 CAS 148147-41-5
| CAS No. | 148147-41-5 |
| Molecular Formula | C43H67NO11 |
| Molecular Weight | 773.99 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Pimecrolimus Impurity 18 (C43H67NO11) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 773.99 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Pimecrolimus Impurity 18 (CAS 148147-41-5, C43H67NO11) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Pimecrolimus Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C43H67NO11 |
| Molecular Weight | 773.99 g/mol |
| Purity | 95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 1 |
Related Pimecrolimus Standards
- Pimecrolimus Impurity 22 (CAS 137712-89-1)
- Pimecrolimus Impurity 7 (CAS CATO-C4X-17317)
- Pimecrolimus Impurity 8 (CAS CATO-C4X-17318)
- Pimecrolimus Impurity 1 (CAS 1025113-89-6)
- Pimecrolimus Impurity 11 (CAS CATO-C4X-173111)
- Pimecrolimus (CAS 137071-32-0)
- Pimecrolimus Impurity 12 (CAS CATO-C4X-173112)
- Pimecrolimus Impurity 13 (CAS CATO-C4X-173113)
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